Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745502 | 0.77 | ALDH1A1 (0.52) | MMP2CA12CA14CA2CA9 | |
| SCHEMBL12463013 | 0.75 | MMP2 (0.47) | PLCG1MMP2CA12CA14CA2 | |
| SCHEMBL152957 | 0.74 | MMP2 (0.53) | PLCG1MMP2CA12CA14CA2 | |
| SCHEMBL6729425 | 0.74 | MMP2 (0.53) | PLCG1MMP2CA12CA14CA2 | |
| SCHEMBL753122 | 0.74 | MMP2 (0.53) | PLCG1MMP2CA12CA14CA2 | |
| SCHEMBL8745537 | 0.72 | ALDH1A1 (0.53) | CA2CA1KMT2AGAA | |
| SCHEMBL12674211 | 0.72 | MMP2 (0.47) | PLCG1MMP2CA12CA14CA2 | |
| SCHEMBL13813079 | 0.72 | MMP2 (0.47) | PLCG1MMP2CA12CA14CA2 | |
| SCHEMBL21921004 | 0.71 | CA12 (0.55) | PLCG1MMP2CA12CA14CA2 | |
| SCHEMBL14850017 | 0.71 | MMP2 (0.50) | PLCG1MMP2CA12CA14CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654149-B1 | POSITIVE-ACTING RADIATION-SENSITIVE MIXTURE AND RECORDING MATERIAL PRODUCED THEREWITH | HOECHST AG (DE) | 1997-02-05 | — | — | EP | disclosed |