SCHEMBL753122

SCHEMBL753122

O=S(=O)(c1ccc(Br)cc1)C(I)I

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 5/20 0.53
CA12 O43570 4/20 0.53
CA14 Q9ULX7 2/20 0.53
CA2 P00918 4/20 0.50
PLCG1 P19174 1/20 0.48
CA9 Q16790 3/20 0.45
CA1 P00915 2/20 0.45
MMP1 P03956 2/20 0.45
MMP9 P14780 2/20 0.45
MMP13 P45452 2/20 0.45
MMP8 P22894 1/20 0.45
F2 P00734 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
IDO1 P14902 1/20 0.41
CYP2A6 P11509 1/20 0.38
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
SLC1A3 P43003 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26460446 0.82 MMP2 (0.50) MMP2CA12CA14CA2PLCG1
SCHEMBL11761525 0.78 CA1 (0.46) MMP2CA12CA14CA2CA9
SCHEMBL6729425 0.76 MMP2 (0.53) MMP2CA12CA14CA2PLCG1
SCHEMBL536323 0.76 ALDH1A1 (0.54) MMP2CA12CA14CA2CA9
SCHEMBL27694463 0.76 GAA (0.54) MMP2CA12CA2CA9CA1
SCHEMBL11764655 0.76 CA1 (0.45) MMP2CA2CA1MMP1MMP9
SCHEMBL152957 0.76 MMP2 (0.53) MMP2CA12CA14CA2PLCG1
SCHEMBL21818 0.76 GAA (0.54) MMP2CA12CA2CA9CA1
SCHEMBL751346 0.76 TSHR (0.54) MMP2CA12CA14CA2CA9
SCHEMBL11761086 0.76 HTR7 (0.43) MMP2CA12CA14CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US claimed
EP-3037993-A1 Method and apparatus for processing user lactate level information Nokia Technologies OY (FI) 2016-06-29 EP disclosed
US-8287631-B2 Compounds for preventing ghost odour THOR GMBH (DE) 2012-10-16 US disclosed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US disclosed
US-20100186631-A1 Compounds for preventing ghost odour THOR GMBH (DE) 2010-07-29 US disclosed
US-4018611-A Non-yellowing antimicrobial compositions comprising diiodomethyl sulfones METALORGANA ETABLISSEMENT (FL) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone MBTD1, MPST, B2M MMP2 3018/4885CA12 3122/4885CA14 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.