Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745755 | 0.88 | ABCC1 (0.59) | CCR4ABCB1ABCC1HTR1AHTR2A | |
| SCHEMBL8745788 | 0.82 | ABCC1 (0.56) | CCR4ABCC1HTR1AHTR2AHTR7 | |
| SCHEMBL8745761 | 0.81 | ABCC1 (0.54) | CCR4ABCB1ABCC1HTR1AHTR2A | |
| SCHEMBL8745799 | 0.81 | ABCC1 (0.55) | CCR4ABCB1ABCC1HTR1AHTR2A | |
| SCHEMBL8745757 | 0.79 | ABCC1 (0.54) | CCR4ABCB1ABCC1HTR1AHTR2A | |
| SCHEMBL8745763 | 0.78 | ADRA1A (0.55) | CCR4ABCC1HTR1AHTR2A | |
| SCHEMBL8745802 | 0.76 | ABCC1 (0.51) | CCR4ABCB1ABCC1KDM4E | |
| SCHEMBL11630455 | 0.76 | TSHR (0.56) | ABCB1SIGMAR1HTR1AHTR2AHTR2C | |
| SCHEMBL8745779 | 0.75 | NPSR1 (0.50) | ABCC1HTR1AHTR2AHTR2CTSHR | |
| SCHEMBL8745807 | 0.74 | ABCC1 (0.49) | CCR4ABCB1ABCC1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |