Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745755 | 0.83 | ABCC1 (0.59) | ABCC1TP53CCR4ALDH1A1MEN1 | |
| SCHEMBL8745802 | 0.82 | ABCC1 (0.51) | ABCC1TP53CCR4ALDH1A1MEN1 | |
| SCHEMBL8745788 | 0.81 | ABCC1 (0.56) | ABCC1TP53CCR4GAADRD2 | |
| SCHEMBL8745757 | 0.80 | ABCC1 (0.54) | ABCC1TP53CCR4ALDH1A1MEN1 | |
| SCHEMBL8745799 | 0.80 | ABCC1 (0.55) | ABCC1TP53CCR4ALDH1A1MEN1 | |
| SCHEMBL8745761 | 0.79 | ABCC1 (0.54) | ABCC1TP53CCR4ALDH1A1LMNA | |
| SCHEMBL8745763 | 0.77 | ADRA1A (0.55) | ABCC1TP53CCR4DRD2 | |
| SCHEMBL8745772 | 0.74 | CCR4 (0.51) | ABCC1CCR4KDM4ESIGMAR1ABCB1 | |
| SCHEMBL8745805 | 0.74 | ALDH1A1 (0.61) | TP53CCR4ALDH1A1MEN1KMT2A | |
| SCHEMBL8745812 | 0.72 | ALDH1A1 (0.67) | TP53CCR4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |