Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87457 | 0.85 | NAALAD2 (0.38) | TSHRLMNATDP1ALDH1A1FFAR1 | |
| SCHEMBL16302334 | 0.81 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL1223994 | 0.78 | LMNA (0.52) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL87467 | 0.75 | LPAR1 (0.44) | TSHRHSD17B10MEN1KMT2ACYP1A2 | |
| SCHEMBL11096370 | 0.72 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL15130876 | 0.72 | HMGCR (0.42) | TSHRTDP1ALDH1A1FFAR1CPT2 | |
| SCHEMBL25307961 | 0.72 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7813622 | 0.72 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL10442148 | 0.72 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL5249605 | 0.72 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173076-A1 | METABOLICALLY STABLE PEPTIDE ANALOGS | UNIV STRASBOURG (FR) | 2023-06-08 | — | — | US | disclosed |
| US-20170355734-A1 | Metabolically Stable Apelin Analogs in the Treatment of Disease Mediated by the Apelin Receptor | UNIVERSITE DE STRASBOURG (FR) | 2017-12-14 | — | — | US | disclosed |
| US-20150112042-A1 | Antigen Delivery Vectors and Constructs | ALTIMMUNE UK LIMITED (GB) | 2015-04-23 | — | — | US | disclosed |
| US-8759281-B2 | Antigen delivery vectors and constructs | IMMUNE TARGETING SYSTEMS LTD. (GB) | 2014-06-24 | — | — | US | disclosed |
| US-20120315293-A1 | Antigen Delivery Vectors and Constructs | IMMUNE TARGETING SYSTEMS LTD. | 2012-12-13 | — | — | US | disclosed |
| US-8129333-B2 | Antigen delivery vectors and constructs | IMMUNE TARGETING SYSTEMS LTD. (GB) | 2012-03-06 | — | — | US | disclosed |
| US-20120034259-A1 | ANTIGEN DELIVERY VECTORS AND CONSTRUCTS | ALTIMMUNE UK LIMITED (GB) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150112042-A1 | Antigen Delivery Vectors and Constructs | LY96, CD74, CD69 | TSHR 3438/4885LMNA 4002/4885NFKB1 681/4885 |
| US-20120315293-A1 | Antigen Delivery Vectors and Constructs | LY96, CD74, CD69 | TSHR 3438/4885LMNA 4002/4885NFKB1 681/4885 |
| US-20170355734-A1 | Metabolically Stable Apelin Analogs in the Treatment of Disease Mediated by the Apelin Receptor | APLNR, AVPR2, AVPR1A | TSHR 297/4885LMNA 2310/4885NFKB1 2735/4885 |
| US-20230173076-A1 | METABOLICALLY STABLE PEPTIDE ANALOGS | GPR119, GLP1R, GIPR | TSHR 346/4885LMNA 4537/4885NFKB1 4262/4885 |
| US-20120034259-A1 | ANTIGEN DELIVERY VECTORS AND CONSTRUCTS | LY96, CD74, CD69 | TSHR 3438/4885LMNA 4002/4885NFKB1 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.