SCHEMBL87457

SCHEMBL87457

CC(F)(F)CC(F)(F)CC(F)(F)CC(F)(F)CCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAALAD2 Q9Y3Q0 1/20 0.38
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
THRB P10828 1/20 0.35
KMT2A Q03164 1/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FFAR3 O14843 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
LMNA P02545 2/20 0.32
ALKBH5 Q6P6C2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87458 0.85 TSHR (0.43) ALDH1A1MEN1CYP1A2KMT2AESR1
SCHEMBL24041181 0.79 LMNA (0.32) NAALAD2ALDH1A1MEN1CYP1A2THRB
SCHEMBL15130876 0.78 HMGCR (0.42) ALDH1A1TSHRHIF1AFFAR1CPT2
SCHEMBL17300290 0.78 HMGCR (0.42) ALDH1A1TSHRHIF1AFFAR1CPT2
SCHEMBL6681107 0.78 NAALAD2 (0.41) NAALAD2ALDH1A1MEN1CYP1A2THRB
SCHEMBL26342933 0.78 LMNA (0.38) NAALAD2ALDH1A1MEN1CYP1A2THRB
SCHEMBL764869 0.77
SCHEMBL12987414 0.77 LMNA (0.47) NAALAD2ALDH1A1MEN1CYP1A2THRB
Hydrochloric Acid SCHEMBL15670496 0.75 NAALAD2 (0.45) NAALAD2ALDH1A1MEN1CYP1A2THRB
SCHEMBL87591 0.74 TSHR (0.32) ALDH1A1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIV STRASBOURG (FR) 2023-06-08 US disclosed
US-11648305-B2 Fluorocarbon-linked peptide formulation Altimmune UK Ltd. (GB) 2023-05-16 US disclosed
US-9962453-B2 Immunogenic compound ALTIMMUNE UK LIMITED (GB) 2018-05-08 US disclosed
US-20170355734-A1 Metabolically Stable Apelin Analogs in the Treatment of Disease Mediated by the Apelin Receptor UNIVERSITE DE STRASBOURG (FR) 2017-12-14 US disclosed
US-20170049898-A1 INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS IMMUNE TARGETING SYSTEMS LIMITED (GB) 2017-02-23 US disclosed
US-20160310603-A1 IMMUNOGENIC COMPOUND ALTIMMUNE UK LIMITED (GB) 2016-10-27 US disclosed
US-9446143-B2 Influenza antigen delivery vectors and constructs ALTIMMUNE UK LIMITED (GB) 2016-09-20 US disclosed
US-20160199469-A1 ONCOLOGY VACCINE ALTIMMUNE UK LIMITED (GB) 2016-07-14 US disclosed
US-20160106830-A1 VACCINES AGAINST HEPATITIS B VIRUS IMMUNE TARGETING SYSTEMS (ITS) LIMITED (GB) 2016-04-21 US disclosed
US-9119811-B2 Fluorocarbon-linked peptide formulation VAXIN UK LIMITED (GB) 2015-09-01 US disclosed
US-20150112042-A1 Antigen Delivery Vectors and Constructs ALTIMMUNE UK LIMITED (GB) 2015-04-23 US disclosed
US-20140234356-A1 INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS IMMUNE TARGETING SYSTEMS LTD. (GB) 2014-08-21 US disclosed
US-8759281-B2 Antigen delivery vectors and constructs IMMUNE TARGETING SYSTEMS LTD. (GB) 2014-06-24 US disclosed
US-20120315293-A1 Antigen Delivery Vectors and Constructs IMMUNE TARGETING SYSTEMS LTD. 2012-12-13 US disclosed
US-8129333-B2 Antigen delivery vectors and constructs IMMUNE TARGETING SYSTEMS LTD. (GB) 2012-03-06 US disclosed
US-20120034259-A1 ANTIGEN DELIVERY VECTORS AND CONSTRUCTS ALTIMMUNE UK LIMITED (GB) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150112042-A1 Antigen Delivery Vectors and Constructs LY96, CD74, CD69 NAALAD2 1404/4885ALDH1A1 3392/4885MEN1 3700/4885
US-20120315293-A1 Antigen Delivery Vectors and Constructs LY96, CD74, CD69 NAALAD2 1404/4885ALDH1A1 3392/4885MEN1 3700/4885
US-20140234356-A1 INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS LY96, CD74, HAVCR2 NAALAD2 771/4885ALDH1A1 2465/4885MEN1 4406/4885
US-20170355734-A1 Metabolically Stable Apelin Analogs in the Treatment of Disease Mediated by the Apelin Receptor APLNR, AVPR2, AVPR1A NAALAD2 191/4885ALDH1A1 1151/4885MEN1 429/4885
US-20160199469-A1 ONCOLOGY VACCINE CD4, CD81, TP53 NAALAD2 3522/4885ALDH1A1 4876/4885MEN1 85/4885
US-20170049898-A1 INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS LY96, CD74, HAVCR2 NAALAD2 771/4885ALDH1A1 2465/4885MEN1 4406/4885
US-20160106830-A1 VACCINES AGAINST HEPATITIS B VIRUS HLA-DRB1, CD4, HLA-B NAALAD2 1649/4885ALDH1A1 4847/4885MEN1 2636/4885
US-11648305-B2 Fluorocarbon-linked peptide formulation VIP, FGB, LNPEP NAALAD2 371/4885ALDH1A1 4489/4885MEN1 319/4885
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS GPR119, GLP1R, GIPR NAALAD2 1261/4885ALDH1A1 3147/4885MEN1 1092/4885
US-20160310603-A1 IMMUNOGENIC COMPOUND CD74, HLA-DRB1, MICA NAALAD2 697/4885ALDH1A1 4489/4885MEN1 3152/4885
US-20120034259-A1 ANTIGEN DELIVERY VECTORS AND CONSTRUCTS LY96, CD74, CD69 NAALAD2 1404/4885ALDH1A1 3392/4885MEN1 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.