Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079563 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL7231294 | 0.76 | MAOA (0.62) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL3796697 | 0.76 | CA12 (0.82) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL15165959 | 0.76 | KDM4E (0.49) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL28787151 | 0.74 | CYP3A4 (0.60) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL9976086 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL4772250 | 0.74 | KDM4E (0.74) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL9319521 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KDM4ECA12CA1CA7 | |
| SCHEMBL4390839 | 0.74 | ALDH1A1 (0.78) | ALDH1A1KDM4EMAOAPOLBGAA | |
| SCHEMBL13924666 | 0.73 | MAOA (0.55) | ALDH1A1KDM4ECA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233523-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS | AMAZENTIS SA (CH) | 2023-07-27 | — | — | US | disclosed |
| US-20230233523-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS | AMAZENTIS SA (CH) | 2023-07-27 | — | — | US | disclosed |
| US-20210353591-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS | AMAZENTIS SA (CH) | 2021-11-18 | — | — | US | disclosed |
| US-11020373-B2 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof | AMAZENTIS SA (CH) | 2021-06-01 | — | — | US | disclosed |
| US-20200397748-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS OR PRECURSORS THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2020-12-24 | — | — | US | disclosed |
| US-9962366-B2 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof | AMAZENTIS SA (CH) | 2018-05-08 | — | — | US | disclosed |
| US-9962366-B2 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof | AMAZENTIS SA (CH) | 2018-05-08 | — | — | US | disclosed |
| US-20180015069-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS OR PRECURSORS THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2018-01-18 | — | — | US | disclosed |
| US-20180015069-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS OR PRECURSORS THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2018-01-18 | — | — | US | disclosed |
| US-20160000753-A1 | Enhancing Autophagy or Increasing Longevity by Administration of Urolithins or Precursors Thereof | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-01-07 | — | — | US | disclosed |
| US-20160000753-A1 | Enhancing Autophagy or Increasing Longevity by Administration of Urolithins or Precursors Thereof | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-01-07 | — | — | US | disclosed |
| US-20140018415-A1 | Enhancing Autophagy or Increasing Longevity by Administration of Urolithins or Precursors Thereof | AMAZENTIS SA (CH) | 2014-01-16 | — | — | US | disclosed |
| US-20140018415-A1 | Enhancing Autophagy or Increasing Longevity by Administration of Urolithins or Precursors Thereof | AMAZENTIS SA (CH) | 2014-01-16 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200397748-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS OR PRECURSORS THEREOF | ATG7, BECN1, ATG4A | ALDH1A1 1860/4885KDM4E 1511/4885CA12 4873/4885 |
| US-20230233523-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS | ATG7, BECN1, ATG4A | ALDH1A1 1735/4885KDM4E 1490/4885CA12 4875/4885 |
| US-11020373-B2 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof | ATG7, BECN1, ATG4A | ALDH1A1 1860/4885KDM4E 1511/4885CA12 4873/4885 |
| US-20160000753-A1 | Enhancing Autophagy or Increasing Longevity by Administration of Urolithins or Precursors Thereof | ATG7, BECN1, ATG4A | ALDH1A1 1860/4885KDM4E 1511/4885CA12 4873/4885 |
| US-20180015069-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS OR PRECURSORS THEREOF | ATG7, BECN1, ATG4A | ALDH1A1 1860/4885KDM4E 1511/4885CA12 4873/4885 |
| US-20140018415-A1 | Enhancing Autophagy or Increasing Longevity by Administration of Urolithins or Precursors Thereof | ATG7, BECN1, ATG4A | ALDH1A1 1860/4885KDM4E 1511/4885CA12 4873/4885 |
| US-20210353591-A1 | ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS | ATG7, BECN1, ATG4A | ALDH1A1 1735/4885KDM4E 1490/4885CA12 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.