Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922845 | 0.83 | CMA1 (0.51) | GAAGFERKDM4EMEN1KMT2A | |
| SCHEMBL2034751 | 0.78 | KDM4E (0.49) | GAAGFERKDM4EALDH1A1SIGMAR1 | |
| SCHEMBL18757774 | 0.74 | ALDH1A1 (0.45) | GAAGFERKDM4EMEN1KMT2A | |
| SCHEMBL1247788 | 0.73 | HPGD (0.47) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18377688 | 0.69 | ALDH1A1 (0.54) | GAAGFERKDM4EMEN1KMT2A | |
| SCHEMBL19732308 | 0.69 | ALDH1A1 (0.54) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1768224 | 0.69 | ALDH1A1 (0.54) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30946374 | 0.69 | TOP2A (0.52) | KDM4EALDH1A1SIGMAR1MAPTALOX15 | |
| SCHEMBL7684043 | 0.69 | ALDH1A1 (0.54) | GAAKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL14987051 | 0.68 | PDE8B (0.46) | GAAGFERKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10729738-B2 | Hindered disulfide drug conjugates | GENENTECH, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2017-04-27 | — | — | US | disclosed |
| WO-2017064675-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| EP-0636934-B1 | Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction | EASTMAN KODAK CO (US) | 1997-02-19 | — | — | EP | disclosed |
| US-5514530-A | IMPROVED COLOR DENSITY, COLOR NEGATIVE FILMS | EASTMAN KODAK COMPANY (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0348139-B1 | Photograhic materials and process | EASTMAN KODAK CO (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0347850-B1 | Photographic material having combination of releasable compounds | EASTMAN KODAK CO (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0636934-A1 | Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction | EASTMAN KODAK COMPANY (US) | 1995-02-01 | — | — | EP | disclosed |
| US-4962018-A | TIMED RELEASE DEVELOPMENT INHIBITOR | EASTMAN KODAK COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4912024-A | Mixture of couplers | EASTMAN KODAK COMPANY (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0348139-A2 | Photograhic materials and process | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10729738-B2 | Hindered disulfide drug conjugates | STS, TST, SCLY | GAA 2778/4885GFER 24/4885KDM4E 3411/4885 |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | STS, TST, SCLY | GAA 2778/4885GFER 24/4885KDM4E 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.