Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
| ▸ | PDCD4 | Q53EL6 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | ACP1 | P24666 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752822 | 0.84 | DAGLA (0.36) | DAGLATOP1PDCD4GPR84FFAR1 | |
| SCHEMBL8985019 | 0.73 | ACHE (0.41) | GPR84PTPN1ACP1CDC25B | |
| SCHEMBL4184971 | 0.69 | ESR1 (0.38) | TOP1GPR84FFAR1 | |
| SCHEMBL7296440 | 0.66 | PDCD4 (0.41) | DAGLAPDCD4GPR84FFAR1 | |
| SCHEMBL23322273 | 0.65 | PDCD4 (0.35) | DAGLATOP1PDCD4GPR84FFAR1 | |
| SCHEMBL27904917 | 0.65 | ACHE (0.50) | TOP1GPR84FFAR1 | |
| SCHEMBL7296014 | 0.65 | PDCD4 (0.47) | DAGLATOP1PDCD4CDC25B | |
| Maleic Anhydride SCHEMBL28269440 | 0.64 | PDCD4 (0.43) | DAGLATOP1PDCD4GPR84FFAR1 | |
| SCHEMBL27460058 | 0.59 | LMNA (0.52) | GPR84FFAR1 | |
| SCHEMBL9840524 | 0.57 | GPR84 (0.50) | GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755389-A1 | 3 AND 5 ALKYL AND PHENYL 4-(HYDROXY OR ACYLOXY)-ALKYL SUBSTITUTED 2(5H)-FURANONES AS ANTI-INFLAMMATORY AGENTS | Allergan (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028394-A1 | 3 AND 5 ALKYL AND PHENYL 4-(HYDROXY OR ACYLOXY)-ALKYL SUBSTITUTED 2(5H)-FURANONES AS ANTI-INFLAMMATORY AGENTS | ALLERGAN (US) | 1995-10-26 | — | — | WO | disclosed |
| US-5451686-A | 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substituted 2(5H)-furanones as anti-inflammatory agents | ALLERGAN, INC. (US) | 1995-09-19 | — | — | US | disclosed |