Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.36 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621126 | 0.75 | ALOX5 (0.44) | ALOX5GLS2PDCD4PRKCDPRKCA | |
| SCHEMBL8616293 | 0.75 | ALOX5 (0.44) | ALOX5GLS2PDCD4PRKCDPRKCA | |
| SCHEMBL7293046 | 0.75 | GLS2 (0.44) | ALOX5GLS2PDCD4FAAH | |
| SCHEMBL7294647 | 0.75 | GLS2 (0.44) | ALOX5GLS2PDCD4FAAH | |
| SCHEMBL11424049 | 0.74 | ALOX5 (0.51) | ALOX5GLS2FAAH | |
| SCHEMBL8653873 | 0.73 | PDCD4 (0.42) | ALOX5GLS2PDCD4FAAH | |
| SCHEMBL8616611 | 0.69 | PDCD4 (0.43) | ALOX5GLS2PDCD4FAAH | |
| SCHEMBL8617164 | 0.69 | PDCD4 (0.43) | ALOX5GLS2PDCD4FAAH | |
| SCHEMBL9340624 | 0.69 | ALDH1A1 (0.49) | — | |
| SCHEMBL27477569 | 0.69 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755389-A1 | 3 AND 5 ALKYL AND PHENYL 4-(HYDROXY OR ACYLOXY)-ALKYL SUBSTITUTED 2(5H)-FURANONES AS ANTI-INFLAMMATORY AGENTS | Allergan (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028394-A1 | 3 AND 5 ALKYL AND PHENYL 4-(HYDROXY OR ACYLOXY)-ALKYL SUBSTITUTED 2(5H)-FURANONES AS ANTI-INFLAMMATORY AGENTS | ALLERGAN (US) | 1995-10-26 | — | — | WO | disclosed |
| US-5451686-A | 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substituted 2(5H)-furanones as anti-inflammatory agents | ALLERGAN, INC. (US) | 1995-09-19 | — | — | US | disclosed |