SCHEMBL8745969

SCHEMBL8745969

O=Cc1ccccc1CC(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 2/20 0.41
HPGD P15428 1/20 0.41
TRIM24 O15164 2/20 0.40
TRIM33 Q9UPN9 2/20 0.40
TSHR P16473 1/20 0.40
ERN1 O75460 2/20 0.35
GAA P10253 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
SRC P12931 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL741192 0.81 LMNA (0.41) LMNAKMT2AMEN1THRBBLM
SCHEMBL7792761 0.79 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL4088533 0.79 LMNA (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL23557596 0.77 MEN1 (0.37) LMNAKMT2AMEN1THRBBLM
SCHEMBL3022708 0.77 ALDH1A1 (0.38) KMT2AMEN1TDP1ALDH1A1
SCHEMBL11717665 0.77 IDO1 (0.38) TDP1ALDH1A1TSHR
SCHEMBL2680152 0.76 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL7453987 0.75 LMNA (0.60) LMNAKMT2AMEN1THRBBLM
SCHEMBL9480041 0.74 CYSLTR2 (0.45) LMNAKMT2AMEN1THRBBLM
SCHEMBL28993114 0.74 PTGER3 (0.56) SMN1; SMN2HTTNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-9872493-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-23 US disclosed
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-29 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 US disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP disclosed
EP-2923573-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
EP-2923574-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
EP-1697354-B1 ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS MERCK SHARP & DOHME (US) 2013-08-07 EP disclosed
EP-0758323-A1 HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF ZENECA LIMITED (GB) 1997-02-19 EP disclosed
EP-0689436-A4 UNIV FLORIDA STATE (US) 1996-02-07 EP disclosed
EP-0689436-A1 TAXANES HAVING ALKOXY, ALKENOXY OR ARYLOXY SUBSTITUTED SIDE-CHAIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME FLORIDA STATE UNIVERSITY (US) 1996-01-03 EP disclosed
US-4946566-A PHOTOREDUCTION OF 9,10-PHENANTHRA-QUINONE AND DERIVATIVES CANADIAN PATENTS & DEVELOPMENT LTD. (CA) 1990-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B LMNA 4787/4885KMT2A 1223/4885MEN1 4418/4885
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, BROX, FGF2 LMNA 4306/4885KMT2A 1800/4885MEN1 3616/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 LMNA 4736/4885KMT2A 407/4885MEN1 4448/4885
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 LMNA 4248/4885KMT2A 2323/4885MEN1 3052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.