Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745946 | 0.86 | KDM4E (0.39) | DYRK3PRKD3MAP4K4CDK1CDK2 | |
| SCHEMBL8745913 | 0.82 | NOTUM (0.36) | DYRK3PRKD3MAP4K4CDK1CDK2 | |
| SCHEMBL8745932 | 0.81 | NOTUM (0.36) | GAADYRK3PRKD3MAP4K4CDK1 | |
| SCHEMBL9270522 | 0.77 | MGLL (0.39) | KMT2A | |
| SCHEMBL8745920 | 0.72 | PIEZO1 (0.38) | GAADYRK3PRKD3MAP4K4CDK1 | |
| SCHEMBL8745960 | 0.70 | SMN1; SMN2 (0.37) | GAANOTUMKDM4EKMT2ASGMS2 | |
| SCHEMBL9028582 | 0.70 | SCN9A (0.40) | NOTUMSCN9ACNR2POLBSLC22A12 | |
| SCHEMBL8745912 | 0.70 | NOTUM (0.40) | GAANOTUMKDM4EKMT2ALMNA | |
| SCHEMBL8745948 | 0.70 | POLB (0.39) | GAAKDM4EKMT2ASGMS2LMNA | |
| SCHEMBL8745957 | 0.69 | SMN1; SMN2 (0.36) | GAAKDM4EKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |