SCHEMBL8746151

SCHEMBL8746151

C=C(C#N)c1ccccc1CCl

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25093172 0.81 GABRA1 (0.39) ALDH1A1TSHRCYP1A1CYP1A2CYP1B1
SCHEMBL5597933 0.77 ALDH1A1 (0.36) ALDH1A1KDM4ETSHRCYP1A1CYP1A2
SCHEMBL13067921 0.77 ALDH1A1 (0.30) ALDH1A1KDM4EGLAGAATSHR
SCHEMBL8746153 0.75 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL7939440 0.74 ALDH1A1 (0.35) ALDH1A1KDM4EGAATSHR
SCHEMBL11357050 0.74 CES2 (0.46) ALDH1A1KDM4ETSHRCYP1A2TRPA1
SCHEMBL2841065 0.74 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL29435253 0.74 CES2 (0.46) ALDH1A1KDM4ETSHRCYP1A2TRPA1
SCHEMBL18645743 0.71 HPGD (0.43) ALDH1A1KDM4EGAATSHR
SCHEMBL24110829 0.71 ALDH1A1 (0.45) ALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602254-B1 POLYMERIZABLE MONOMER, POLYMER THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KK (JP) 1997-01-02 EP disclosed
EP-0602254-A1 POLYMERIZABLE MONOMER, POLYMER THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1994-06-22 EP disclosed