SCHEMBL8746153

SCHEMBL8746153

C=C(Cl)c1ccccc1CCl

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
FOLH1 Q04609 1/20 0.31
ALOX15 P16050 1/20 0.31
HSPA5 P11021 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
AURKA O14965 1/20 0.30
AURKB Q96GD4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2841065 0.80 ALDH1A1 (0.35) ALDH1A1TSHRFOLH1HSPA5
SCHEMBL7939440 0.80 ALDH1A1 (0.35) ALDH1A1TSHRFOLH1ALOX15HSPA5
SCHEMBL152624 0.77 ALDH1A1 (0.50) ALDH1A1TSHRFOLH1ALOX15L3MBTL1
Methylene Chloride SCHEMBL29209400 0.76 ALDH1A1 (0.48) ALDH1A1TSHRFOLH1ALOX15L3MBTL1
SCHEMBL8746151 0.75 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL3145510 0.74 ALDH1A1 (0.42) ALDH1A1TSHRFOLH1ALOX15L3MBTL1
SCHEMBL7157502 0.74 ALDH1A1 (0.39) ALDH1A1TSHRFOLH1ALOX15KMT2A
Ethylene SCHEMBL27801534 0.74 FOLH1 (0.55) ALDH1A1TSHRFOLH1ALOX15KMT2A
SCHEMBL28173435 0.74 LIPG (0.44) TSHRL3MBTL1
SCHEMBL602386 0.73 FOLH1 (0.59) ALDH1A1TSHRFOLH1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602254-B1 POLYMERIZABLE MONOMER, POLYMER THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KK (JP) 1997-01-02 EP disclosed
EP-0602254-A1 POLYMERIZABLE MONOMER, POLYMER THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1994-06-22 EP disclosed