Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674128 | 0.78 | ALDH1A1 (0.51) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL9175317 | 0.75 | CNR1 (0.39) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL7764412 | 0.70 | S1PR1 (0.55) | ALDH1A1KDM4EGAAEPHX1KMT2A | |
| SCHEMBL8858684 | 0.70 | CNR1 (0.44) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL5676704 | 0.69 | KDM4E (0.52) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL29779677 | 0.68 | S1PR1 (0.52) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL8746156 | 0.68 | KDM4E (0.39) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL27405022 | 0.68 | EPHX1 (0.38) | ALDH1A1KDM4EGAAEPHX1KMT2A | |
| SCHEMBL7019900 | 0.65 | CD38 (0.57) | CNR1ALDH1A1KDM4EGAAEPHX1 | |
| SCHEMBL1416341 | 0.65 | HSP90AA1 (0.52) | ALDH1A1HPGDKDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643702-B1 | 4-PYRIMIDINE SULFENAMIDES AND THEIR USE IN RUBBER | MONSANTO CO (US) | 1997-01-02 | — | — | EP | claimed |
| EP-0643702-A1 | 4-PYRIMIDINE SULFENAMIDES AND THEIR USE IN RUBBER. | MONSANTO CO (US) | 1995-03-22 | — | — | EP | claimed |
| WO-1993025538-A1 | 4-PYRIMIDINE SULFENAMIDES AND THEIR USE IN RUBBER | MONSANTO COMPANY (US) | 1993-12-23 | — | — | WO | claimed |
| EP-0643702-B1 | 4-PYRIMIDINE SULFENAMIDES AND THEIR USE IN RUBBER | MONSANTO CO (US) | 1997-01-02 | — | — | EP | disclosed |
| EP-0643702-A1 | 4-PYRIMIDINE SULFENAMIDES AND THEIR USE IN RUBBER. | MONSANTO CO (US) | 1995-03-22 | — | — | EP | disclosed |
| WO-1993025538-A1 | 4-PYRIMIDINE SULFENAMIDES AND THEIR USE IN RUBBER | MONSANTO COMPANY (US) | 1993-12-23 | — | — | WO | disclosed |