Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674128 | 0.78 | ALDH1A1 (0.51) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL8746162 | 0.70 | CNR1 (0.41) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL5676704 | 0.69 | KDM4E (0.52) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL8858661 | 0.68 | GOT1 (0.35) | — | |
| SCHEMBL9175317 | 0.68 | CNR1 (0.39) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL6024930 | 0.67 | ALDH1A1 (0.49) | ALDH1A1HPGDTDP1KDM4EGAA | |
| SCHEMBL31119419 | 0.67 | CYP11B2 (0.46) | ALDH1A1KDM4EGAAOPRK1RAB9A | |
| SCHEMBL277675 | 0.67 | CYP11B2 (0.46) | ALDH1A1KDM4EGAAOPRK1RAB9A | |
| SCHEMBL28426800 | 0.67 | NPC1 (0.47) | CNR1ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL1111756 | 0.65 | ALDH1A1 (0.46) | CNR1ALDH1A1HPGDTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644881-B1 | 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER | MONSANTO CO (US) | 1997-07-30 | — | — | EP | claimed |
| WO-1993025537-A1 | 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER | MONSANTO COMPANY (US) | 1993-12-23 | — | — | WO | claimed |
| EP-0644881-B1 | 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER | MONSANTO CO (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0726255-A2 | 3-Pyridazine derivatives and their use in rubber | MONSANTO COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1993025537-A1 | 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER | MONSANTO COMPANY (US) | 1993-12-23 | — | — | WO | disclosed |