Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277874 | 1.00 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9333256 | 1.00 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9333564 | 1.00 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9333587 | 1.00 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9333535 | 1.00 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL540169 | 1.00 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL163984 | 0.93 | — | — | |
| SCHEMBL1063406 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28555010 | 0.87 | EPHX2 (0.42) | TSHRALDH1A1ABCB11CYP3A4ADRA2B | |
| SCHEMBL7878546 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | ARIAGEN, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20200157053-A1 | Method of Treating or Inhibiting Malaria | UNIV OREGON HEALTH & SCIENCE (US) | 2020-05-21 | — | — | US | disclosed |
| US-10584098-B2 | Quinolone-3-diarylethers | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-03-10 | — | — | US | disclosed |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-09-19 | — | — | US | disclosed |
| US-20180362465-A1 | QUINOLONE-3-DIARYLETHERS | UNIV OREGON HEALTH & SCIENCE (US) | 2018-12-20 | — | — | US | disclosed |
| WO-2017015360-A1 | QUINOLONE-3-DIARYLETHERS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-01-26 | — | — | WO | disclosed |
| US-20170022164-A1 | QUINOLONE-3-DIARYLETHERS | UNIV OREGON HEALTH & SCIENCE (US) | 2017-01-26 | — | — | US | disclosed |
| US-20130096088-A1 | Inhibitors of Protein Tyrosine Kinase Activity | METHYLGENE INC. (CA) | 2013-04-18 | — | — | US | disclosed |
| US-20130096088-A1 | Inhibitors of Protein Tyrosine Kinase Activity | METHYLGENE INC. (CA) | 2013-04-18 | — | — | US | disclosed |
| WO-2013044361-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| EP-0619320-B1 | 5-O-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5631354-A | ERYTHROMYCIN DERIVATIVES WITH IMPROVED ANTIBACTERIAL ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0619319-B1 | 5-0-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5523399-A | MACROLIDE ANTIBIOTICS HAVING A STRONG ANTIBACTERIAL ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0619319-A1 | 5-0-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0619320-A1 | 5-O-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5350839-A | Esters to improve taste and remove bitterness | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0553353-A1 | 2'-MODIFIED ERYTHROMYCIN OR DERIVATIVE THEREOF | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | TSHR 41/4885ALDH1A1 488/4885TP53 1114/4885 |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | AHR, ARNT, CNR1 | TSHR 31/4885ALDH1A1 630/4885TP53 2505/4885 |
| US-20180362465-A1 | QUINOLONE-3-DIARYLETHERS | RECQL, ELANE, ELF3 | TSHR 4838/4885ALDH1A1 2150/4885TP53 1929/4885 |
| US-20170022164-A1 | QUINOLONE-3-DIARYLETHERS | RECQL, ELANE, ELF3 | TSHR 4838/4885ALDH1A1 2150/4885TP53 1929/4885 |
| US-10584098-B2 | Quinolone-3-diarylethers | RECQL, ELANE, ELF3 | TSHR 4838/4885ALDH1A1 2150/4885TP53 1929/4885 |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | TSHR 41/4885ALDH1A1 488/4885TP53 1013/4885 |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR, ARNT, CNR1 | TSHR 31/4885ALDH1A1 630/4885TP53 2505/4885 |
| US-20130096088-A1 | Inhibitors of Protein Tyrosine Kinase Activity | KDR, FLT1, FLT4 | TSHR 766/4885ALDH1A1 4375/4885TP53 573/4885 |
| US-20200157053-A1 | Method of Treating or Inhibiting Malaria | ELANE, ELF3, ELOB | TSHR 4588/4885ALDH1A1 2432/4885TP53 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.