SCHEMBL8747626

SCHEMBL8747626

Cc1cc(O)c(C(C)(C)C)cc1CN

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.52
ALDH1A1 P00352 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
CYP1A2 P05177 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
ATP2A2 P16615 1/20 0.52
ATP2A3 Q93084 1/20 0.52
TP53 P04637 4/20 0.52
HIF1A Q16665 4/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 1/20 0.52
CYP2C9 P11712 6/20 0.47
CYP2C19 P33261 5/20 0.47
CYP2D6 P10635 2/20 0.47
HSD17B10 Q99714 2/20 0.41
LMNA P02545 2/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68939 0.84 ALDH1A1 (0.56) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL9230440 0.84 ALOX15 (0.56) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL30807859 0.84 ALDH1A1 (0.56) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL4066413 0.82 ALOX15 (0.54) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL16688135 0.82 ALOX15 (0.54) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL5073267 0.81 ALOX15 (0.52) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL2163484 0.81 ALOX15 (0.52) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL30471645 0.81 ALOX15 (0.52) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL6537028 0.79 ALOX15 (0.54) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL13310903 0.79 CYP2C9 (0.56) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed