SCHEMBL8747725

SCHEMBL8747725

Nc1cc(S(=O)(=O)O)c2c(O)cccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.51
AURKB Q96GD4 1/20 0.51
PLAU P00749 1/20 0.47
ALDH1A1 P00352 6/20 0.44
APOBEC3G Q9HC16 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
DNMT1 P26358 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
MCL1 Q07820 1/20 0.44
TDP1 Q9NUW8 4/20 0.42
HSD17B10 Q99714 3/20 0.42
CASP7 P55210 2/20 0.42
CASP1 P29466 1/20 0.42
DUSP5 Q16690 1/20 0.42
NSD2 O96028 3/20 0.41
CASP6 P55212 3/20 0.41
TSHR P16473 2/20 0.41
DUSP3 P51452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28065900 0.86 TTR (0.44) AURKAAURKBPLAUALDH1A1APOBEC3G
SCHEMBL2875633 0.81 ALDH1A1 (0.55) AURKAAURKBALDH1A1APOBEC3GMEN1
SCHEMBL29495118 0.79 MEN1 (0.52) AURKAAURKBPLAUALDH1A1APOBEC3G
SCHEMBL465006 0.78 CDK2 (0.53) AURKAAURKBALDH1A1APOBEC3GMEN1
SCHEMBL9681579 0.78 TTR (0.47) AURKAAURKBPLAUALDH1A1APOBEC3G
SCHEMBL2161129 0.78 AURKA (0.49) AURKAAURKBPLAUALDH1A1APOBEC3G
SCHEMBL4383279 0.78 AURKA (0.49) AURKAAURKBPLAUALDH1A1APOBEC3G
SCHEMBL10354361 0.77 CDK2 (0.51) AURKAAURKBALDH1A1APOBEC3GMEN1
SCHEMBL9340309 0.77 NT5E (0.65) ALDH1A1TDP1HSD17B10CASP7CASP1
SCHEMBL10715118 0.76 ALDH1A1 (0.56) PLAUALDH1A1APOBEC3GMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5648841-A Apparatus for forming fixed images having encapsulated toner KAO CORPORATION (JP) 1997-07-15 US disclosed
EP-0516062-B1 Method of forming fixed images KAO CORP (JP) 1997-04-23 EP disclosed
EP-0546514-B1 Encapsulated toner for heat-and-pressure fixing and method for production thereof KAO CORP (JP) 1997-03-12 EP disclosed
US-5463454-A Method of forming fixed images using encapsulated toner KAO CORPORATION (JP) 1995-10-31 US disclosed
US-5436104-A Method of forming fixed images using heated belt KAO CORPORATION (JP) 1995-07-25 US disclosed
US-5376490-A Forming shell-core polymers of addition polymers and polyurethanes and polythiourethanes; core having anhydride groups KAO CORPORATION (JP) 1994-12-27 US disclosed
US-5350658-A Method of forming fixed images comprising simultaneous transfer and fixing of image KAO CORPORATION (JP) 1994-09-27 US disclosed
US-5316885-A THERMAL TRANSFER PRINTING KAO CORPORATION (JP) 1994-05-31 US disclosed
EP-0592675-A1 METHOD OF FORMING FIXED IMAGES Kao Corporation (JP) 1994-04-20 EP disclosed
EP-0586699-A1 METHOD FOR FORMING FIXED IMAGES Kao Corporation (JP) 1994-03-16 EP disclosed
EP-0531888-A2 Method of forming fixed images KAO CORPORATION (JP) 1993-03-17 EP disclosed
WO-1993000616-A1 METHOD OF FORMING FIXED IMAGES KAO CORPORATION (JP) 1993-01-07 WO disclosed
WO-1992022018-A1 METHOD OF FORMING FIXED IMAGES KAO CORPORATION (JP) 1992-12-10 WO disclosed
WO-1992022017-A1 METHOD FOR FORMING FIXED IMAGES KAO CORPORATION (JP) 1992-12-10 WO disclosed
EP-0516062-A2 Method of forming fixed images KAO CORPORATION (JP) 1992-12-02 EP disclosed
EP-0514843-A1 Encapsulated toner for heat and-pressure fixing Kao Corporation (JP) 1992-11-25 EP disclosed
EP-0501673-A1 Encapsulated toner for heat pressure fixing Kao Corporation (JP) 1992-09-02 EP disclosed
EP-0472106-A2 Pulverulent ink and printing methods KAO CORPORATION (JP) 1992-02-26 EP disclosed
EP-0453857-A1 Encapsulated toner for heat-and-pressure fixing KAO CORPORATION (JP) 1991-10-30 EP disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed