Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053771 | 0.85 | GRIN2D (0.50) | PNMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13148540 | 0.81 | PNMT (0.39) | PNMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9147001 | 0.76 | GRIN2D (0.55) | PNMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10455063 | 0.75 | ESR2 (0.55) | — | |
| SCHEMBL9451488 | 0.75 | ALDH1A1 (0.34) | PNMTOPRM1 | |
| SCHEMBL22347856 | 0.75 | KMT2A (0.42) | PNMTOPRL1OPRM1OPRK1MAOB | |
| SCHEMBL22348038 | 0.73 | ESR2 (0.39) | — | |
| SCHEMBL6939188 | 0.72 | GRIN2D (0.57) | PNMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL181479 | 0.72 | GRIN2D (0.62) | PNMTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL346575 | 0.72 | PNMT (0.54) | PNMTGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4398803-A | Liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-08-16 | — | — | US | claimed |
| JP-6228044-A | — | — | None | — | — | JP | disclosed |
| JP-6228044-A | — | — | None | — | — | JP | disclosed |
| EP-3071541-B1 | SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM | UNIV MARQUETTE (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | disclosed |
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | disclosed |
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |
| EP-0532511-B1 | TRETRA-SUBSTITUTED METHANES WITH LIQUID CRYSTAL PROPERTIES | CONSORTIUM ELEKTROCHEM IND (DE) | 1994-11-02 | — | — | EP | disclosed |
| JP-H06228044-A | NEW 1-PHENYLBICYCLO(2,2,2)OCTANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THESE DERIVATIVES | ADIR | 1994-08-16 | — | — | JP | disclosed |
| JP-H06228044-A | NEW 1-PHENYLBICYCLO(2,2,2)OCTANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THESE DERIVATIVES | ADIR | 1994-08-16 | — | — | JP | disclosed |
| US-5326495-A | Tetrasubstituted methanes having liquid-crystalline properties | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-07-05 | — | — | US | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |
| EP-0532511-A1 | TRETRA-SUBSTITUTED METHANES WITH LIQUID CRYSTAL PROPERTIES. | CONSORTIUM ELEKTROCHEM IND (DE) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991016295-A1 | TRETRA-SUBSTITUTED METHANES WITH LIQUID CRYSTAL PROPERTIES | Consortium für elektrochemische Industrie GmbH (DE) | 1991-10-31 | — | — | WO | disclosed |
| US-4595521-A | In liquid crystalline carrier | HOFFMANN-LA ROCHE INC. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4452718-A | Pyridazines | HOFFMANN-LA ROCHE INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4419262-A | Pyridazines | HOFFMANN-LA ROCHE INC. (US) | 1983-12-06 | — | — | US | disclosed |
| US-4398803-A | Liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-08-16 | — | — | US | disclosed |