Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21935248 | 0.77 | ACHE (0.59) | MAOBMAOASLC6A3SLC6A2ACHE | |
| SCHEMBL8747847 | 0.77 | MAOB (0.38) | OPRM1OPRK1OPRL1MAOBMAOA | |
| SCHEMBL8178693 | 0.77 | OPRM1 (0.44) | OPRM1OPRK1OPRL1MAOBMAOA | |
| SCHEMBL2640740 | 0.73 | OPRM1 (0.63) | OPRM1OPRK1OPRL1MAOBMAOA | |
| SCHEMBL21264045 | 0.73 | OPRM1 (0.42) | OPRM1OPRK1OPRL1MAOBMAOA | |
| SCHEMBL10021108 | 0.70 | OPRM1 (0.55) | OPRM1OPRK1OPRL1MAOBMAOA | |
| SCHEMBL11962271 | 0.70 | OPRM1 (0.55) | OPRM1OPRK1OPRL1MAOBMAOA | |
| SCHEMBL21935244 | 0.69 | ALDH1A1 (0.46) | MAOBMAOAKMT2AMEN1 | |
| SCHEMBL22113157 | 0.68 | MAOB (0.42) | OPRM1OPRK1OPRL1MAOBMAOA | |
| SCHEMBL893223 | 0.68 | OPRM1 (0.53) | OPRM1OPRK1OPRL1OPRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | disclosed |
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |