SCHEMBL8748008

SCHEMBL8748008

CCCN(CCC)CCC(=O)NCCO

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SELP P16109 1/20 0.49
NAAA Q02083 1/20 0.47
DNM1 Q05193 1/20 0.46
ALDH1A1 P00352 4/20 0.45
CNR1 P21554 4/20 0.45
MEN1 O00255 2/20 0.45
BLM P54132 2/20 0.45
KMT2A Q03164 2/20 0.45
TRPV1 Q8NER1 2/20 0.45
TRPM8 Q7Z2W7 1/20 0.45
FAAH O00519 1/20 0.45
KCNK3 O14649 1/20 0.45
CNR2 P34972 1/20 0.45
HPGD P15428 2/20 0.44
MAPT P10636 1/20 0.44
ALOX12 P18054 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL889136 0.88 MCL1 (0.48) NAAADNM1CNR1MEN1KMT2A
SCHEMBL13469081 0.86 GAA (0.46) SELPNAAADNM1ALDH1A1CNR1
SCHEMBL4579500 0.86 GAA (0.50) SELPNAAADNM1ALDH1A1CNR1
SCHEMBL10657598 0.86 CNR1 (0.41) SELPNAAADNM1ALDH1A1CNR1
SCHEMBL24412931 0.85 CASP2 (0.60) NAAADNM1MEN1KMT2AFAAH
SCHEMBL17453102 0.85 DNM1 (0.47) NAAADNM1CNR1KMT2AFAAH
SCHEMBL19732503 0.84 CNR1 (0.40) SELPNAAADNM1ALDH1A1CNR1
SCHEMBL8747851 0.84 DNM1 (0.68) NAAADNM1FAAH
SCHEMBL10099851 0.83 DNM1 (0.42) NAAADNM1FAAH
SCHEMBL889237 0.82 NAAA (0.63) SELPNAAADNM1CNR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619295-B1 PROCESS FOR PRODUCING N-MONOSUBSTITUTED (METH)ACRYLAMYDE KOHJIN CO (JP) 1997-03-12 EP disclosed
US-5587515-A Method of manufacturing N-monosubstituted (meth)acrylamides KOHJIN CO., LTD. (JP) 1996-12-24 US disclosed
EP-0619295-A1 PROCESS FOR PRODUCING N-MONOSUBSTITUTED (METH)ACRYLAMYDE KOHJIN CO. Ltd. (JP) 1994-10-12 EP disclosed