Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
| ▸ | HRH2 | P25021 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778067 | 0.98 | HRH3 (0.58) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL6731770 | 0.98 | HRH3 (0.58) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL6709103 | 0.94 | MMP3 (0.59) | HRH3ALDH1A1MMP3HRH2HRH1 | |
| SCHEMBL1714609 | 0.94 | HRH3 (0.54) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL5519875 | 0.91 | HRH3 (0.62) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL7447851 | 0.89 | ALDH1A1 (0.53) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL7387284 | 0.89 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL7983991 | 0.89 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL5526919 | 0.89 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3HRH2 | |
| SCHEMBL12408526 | 0.89 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601977-B1 | Aromatic hydroxyamidine derivatives and their use as leukotriene B4 receptor antagonists | CIBA GEIGY AG (CH) | 1997-01-22 | — | — | EP | disclosed |
| US-5455274-A | Leukotriene antagonists; treating rheumatoid arthritis | CIBA-GEIGY CORPORATION (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0601977-A1 | Aromatic hydroxyamidine derivatives and their use as leukotriene B4 receptor anagonists | CIBA-GEIGY AG (CH) | 1994-06-15 | — | — | EP | disclosed |