Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CDC25B | P30305 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315559 | 0.89 | TSHR (0.54) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL8648602 | 0.82 | NR4A2 (0.46) | TSHRALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9115108 | 0.82 | ALDH1A1 (0.54) | TSHRALDH1A1HPGD | |
| SCHEMBL29671336 | 0.79 | TSHR (0.73) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL2569253 | 0.79 | TSHR (0.73) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL11273803 | 0.77 | TSHR (0.63) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL4319548 | 0.76 | KDM4E (0.42) | TSHRALDH1A1KDM4EMAOBGAA | |
| SCHEMBL9150759 | 0.76 | TSHR (0.73) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL249780 | 0.74 | NR4A1 (0.48) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL28416763 | 0.73 | TSHR (0.63) | TSHRCDC25BALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534257-B1 | Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof | MITSUI TOATSU CHEMICALS (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5306688-A | Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0534257-A1 | Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-03-31 | — | — | EP | disclosed |