Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM6A | O15550 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966245 | 0.86 | NR4A1 (0.52) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL5213229 | 0.83 | AKR1C3 (0.46) | ALDH1A1KDM4EHSD17B10CYP2C9L3MBTL1 | |
| SCHEMBL4319548 | 0.82 | KDM4E (0.42) | ALDH1A1KDM4EHPGDTSHRL3MBTL1 | |
| SCHEMBL249202 | 0.82 | ATM (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL8648602 | 0.78 | NR4A2 (0.46) | NR4A2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8904316 | 0.76 | F2 (0.37) | WDR5PKMKMT2A | |
| SCHEMBL29043434 | 0.76 | NR4A1 (0.53) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL9115108 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP2C9TSHREGLN1 | |
| SCHEMBL297787 | 0.75 | NR4A1 (0.44) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL8748348 | 0.74 | TSHR (0.56) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101925658-B | Anthrapyridone compound or salt thereof, magenta ink composition containing anthrapyridone compound, and colored body | NIPPON KAYAKU KK | 2013-10-02 | — | — | CN | claimed |
| EP-1339663-B1 | NAPHTHALENE DERIVATIVES | NOVARTIS AG (CH) | 2012-01-04 | — | — | EP | claimed |
| US-20060025345-A1 | Substituted ethane-1,2-diamines for the treatment of Alzheimer's disease | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-02 | — | — | US | claimed |
| WO-1995015325-A1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-08 | — | — | WO | claimed |
| US-5395847-A | Angiotensin II receptor antagonists; useful in regulating hypertension, treatment of congestive heart failure, renal failure, and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-07 | — | — | US | claimed |
| US-10449168-B2 | Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors | THE UNIVERSITY OF TOLEDO (US) | 2019-10-22 | — | — | US | disclosed |
| US-20180250252-A1 | POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS | THE UNIVERSITY OF TOLEDO (US) | 2018-09-06 | — | — | US | disclosed |
| CN-104955332-B | The method of preventing and treating arthropod insect | 住友化学株式会社 | 2017-03-29 | — | — | CN | disclosed |
| WO-2017040376-A1 | POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS | THE UNIVERSITY OF TOLEDO (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20160229784-A1 | PROCESSES FOR MAKING CYCLOHEXANE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2016-08-11 | — | — | US | disclosed |
| US-20160229774-A1 | PROCESSES FOR MAKING CYCLOHEXANE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2016-08-11 | — | — | US | disclosed |
| US-9346737-B2 | Processes for making cyclohexane compounds | EASTMAN CHEMICAL COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| EP-0256781-A2 | Silver halide light-sensitive color photographic material suitable for rapid processing | KONICA CORPORATION (JP) | 1988-02-24 | — | — | EP | disclosed |
| US-4695530-A | PYRAZOLOAZOLE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0228299-A2 | Silver halide grains, lightsensitive photographic material containing the same and method for preparing silver halide photographic emulsion containing the same | KONICA CORPORATION (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0199351-A2 | Silver halide photographic material | KONICA CORPORATION (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0171238-A2 | Silver halide grains, preparation thereof and light-sensitive photographic material containing said grains | KONICA CORPORATION (JP) | 1986-02-12 | — | — | EP | disclosed |
| US-4542094-A | HYDROXYTETRAZAINDENES AND MERCAPTO-NITROGENCONTAINING HETEROCYLIC COMPOUNDS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-09-17 | — | — | US | disclosed |
| US-4260816-A | HYPOGLYCEMIC, HYPOLIPIDEMIC AGENTS, TREATMENT OF DIABETES | AMERICAN CYANAMID COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4078937-A | SULFUR, HYDROXYTETRAAZAINDENE | FUJI PHOTO FILM CO., LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025345-A1 | Substituted ethane-1,2-diamines for the treatment of Alzheimer's disease | PSEN1, PSEN2, APP | NR4A1 257/4885NR4A2 406/4885NR4A3 351/4885 |
| US-20160229774-A1 | PROCESSES FOR MAKING CYCLOHEXANE COMPOUNDS | DHPS, HPD, HAAO | NR4A1 3638/4885NR4A2 3918/4885NR4A3 3894/4885 |
| US-10449168-B2 | Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors | NAT1, SAT1, NAALAD2 | NR4A1 1329/4885NR4A2 1025/4885NR4A3 1105/4885 |
| US-20180250252-A1 | POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS | NAT1, SAT1, NAALAD2 | NR4A1 1329/4885NR4A2 1025/4885NR4A3 1105/4885 |
| US-20160229784-A1 | PROCESSES FOR MAKING CYCLOHEXANE COMPOUNDS | DHPS, HPD, HAAO | NR4A1 3638/4885NR4A2 3918/4885NR4A3 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.