SCHEMBL8749128

SCHEMBL8749128

FC(F)(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293078 0.87
SCHEMBL632568 0.87 ALDH1A1 (0.30)
SCHEMBL4922320 0.87 ALDH1A1 (0.30)
SCHEMBL8469138 0.87 ALDH1A1 (0.30)
SCHEMBL5729793 0.82 ALDH1A1 (0.33)
SCHEMBL8900702 0.80 LMNA (0.44)
SCHEMBL632567 0.80 LMNA (0.44)
SCHEMBL10797991 0.80 LMNA (0.44)
SCHEMBL8958714 0.77
SCHEMBL1990770 0.77 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0642364-A1 METHOD AND APPARATUS FOR EXTRACORPOREAL SEPARATION OF FLUOROCHEMICALS FROM WHOLE BLOOD OF A PATIENT. HEMAGEN PFC (US) 1995-03-15 EP claimed
US-5295953-A Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient HEMAGEN/PFC (US) 1994-03-22 US claimed
WO-1993024158-A1 METHOD AND APPARATUS FOR EXTRACORPOREAL SEPARATION OF FLUOROCHEMICALS FROM WHOLE BLOOD OF A PATIENT HEMAGEN/PFC (US) 1993-12-09 WO claimed
EP-0642364-B1 APPARATUS FOR EXTRACORPOREAL SEPARATION OF FLUOROCHEMICALS FROM WHOLE BLOOD OF A PATIENT HEMAGEN PFC (US) 1997-03-19 EP disclosed
US-5295953-A Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient HEMAGEN/PFC (US) 1994-03-22 US disclosed
WO-1993024158-A1 METHOD AND APPARATUS FOR EXTRACORPOREAL SEPARATION OF FLUOROCHEMICALS FROM WHOLE BLOOD OF A PATIENT HEMAGEN/PFC (US) 1993-12-09 WO disclosed