SCHEMBL8900702

SCHEMBL8900702

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10797991 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL632567 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL708773 0.96 LMNA (0.39) LMNATHRB
SCHEMBL9580829 0.85 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL379028 0.84 LMNA (0.33) LMNA
SCHEMBL8469138 0.83 ALDH1A1 (0.30) LMNA
SCHEMBL11693903 0.80 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL8675830 0.80 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL8749128 0.80
SCHEMBL6846353 0.80 LMNA (0.47) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5557019-A HALOGENATION, REDUCTION DAIKIN INDUSTRIES LTD. (JP) 1996-09-17 US claimed
EP-0633237-B1 PROCESS FOR PRODUCING 1,1,1,2,2,4,4,5,5,5-DECAFLUOROPENTANE DAIKIN IND LTD (JP) 1997-10-08 EP disclosed
EP-0633237-B1 PROCESS FOR PRODUCING 1,1,1,2,2,4,4,5,5,5-DECAFLUOROPENTANE DAIKIN IND LTD (JP) 1997-10-08 EP disclosed
US-5557019-A HALOGENATION, REDUCTION DAIKIN INDUSTRIES LTD. (JP) 1996-09-17 US disclosed
US-5557019-A HALOGENATION, REDUCTION DAIKIN INDUSTRIES LTD. (JP) 1996-09-17 US disclosed
US-5430203-A Process for the reduction of halocarbons IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-07-04 US disclosed
EP-0633237-A4 1995-01-18 EP disclosed
EP-0633237-A1 PROCESS FOR PRODUCING 1,1,1,2,2,4,4,5,5,5-DECAFLUOROPENTANE DAIKIN INDUSTRIES, LIMITED (JP) 1995-01-11 EP disclosed
EP-0633237-A1 PROCESS FOR PRODUCING 1,1,1,2,2,4,4,5,5,5-DECAFLUOROPENTANE DAIKIN INDUSTRIES, LIMITED (JP) 1995-01-11 EP disclosed
WO-1993016973-A1 PROCESS FOR PRODUCING 1,1,1,2,2,4,4,5,5,5-DECAFLUOROPENTANE DAIKIN INDUSTRIES, LTD. (JP) 1993-09-02 WO disclosed
EP-0386346-A1 Solvent composition for cleaning silicon wafers PCR GROUP, INC. (US) 1990-09-12 EP disclosed
US-4828751-A FLUORINATED ALCOHOL AND PERHALOALKANE PCR, INC. (US) 1989-05-09 US disclosed
EP-0170405-B1 NONSMEARING CORRECTION FLUID MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-08-03 EP disclosed
US-4654081-A Nonsmearing correction fluid MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-31 US disclosed