SCHEMBL8749364

SCHEMBL8749364

Oc1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.61
FFAR1 O14842 3/20 0.51
STK39 Q9UEW8 2/20 0.50
MEN1 O00255 1/20 0.50
TTR P02766 1/20 0.50
PPOX P50336 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MRGPRX4 Q96LA9 10/20 0.48
MAPT P10636 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10538095 0.89 NPSR1 (0.57) RAB9AFFAR1STK39MEN1TTR
SCHEMBL11648951 0.85 FFAR1 (0.50) FFAR1STK39MEN1TTRPPOX
SCHEMBL9711445 0.84 FFAR1 (0.53) RAB9AFFAR1STK39MEN1TTR
SCHEMBL32669004 0.84 FFAR1 (0.55) FFAR1STK39MEN1TTRPPOX
SCHEMBL9132379 0.84 FFAR1 (0.49) RAB9AFFAR1STK39MEN1TTR
SCHEMBL10615136 0.84 FFAR1 (0.55) RAB9AFFAR1STK39MEN1TTR
SCHEMBL9572372 0.84 NPSR1 (0.49) RAB9ASTK39MEN1KMT2AMAPT
SCHEMBL8684467 0.83 FFAR1 (0.61) RAB9AFFAR1MEN1TTRPPOX
SCHEMBL9003844 0.83 FFAR1 (0.60) RAB9AFFAR1MEN1TTRPPOX
SCHEMBL11090445 0.82 NPSR1 (0.49) RAB9ASTK39MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6032758-A None JP disclosed
JP-55154953-A None JP disclosed
JP-5262689-A None JP disclosed
JP-55094353-A None JP disclosed
JP-5262688-A None JP disclosed
JP-4066548-A None JP disclosed
CN-106029890-B Plants with enhanced tolerance to herbicides 巴斯夫农业公司 2022-04-12 CN disclosed
EP-0768085-A1 ANTIBACTERIAL AGENT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-04-16 EP disclosed
EP-0761215-A1 ANTIBACTERIAL AGENT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-03-12 EP disclosed
JP-H0632758-A PRODUCTION OF ALDEHYDE DERIVATIVE TEIJIN LTD 1994-02-08 JP disclosed
US-4330324-A PREEMERGENCE APPLICATION ROHM AND HAAS COMPANY (US) 1982-05-18 US disclosed
EP-0001641-B1 2-(2'-NITRO-5-(2\"-CHLORO-4\"-TRIFLUOROMETHYLPHENOXY)-PHENOXY)-PROPIONIC ACID-METHOXYETHYESTER, A COMPOSITION CONTAINING THIS ESTER AS ACTIVE INGREDIENT AND ITS USE AS A HERBICIDE. CIBA-GEIGY AG (CH) 1981-11-18 EP disclosed
JP-S55154953-A DIPHENYL ETHER DERIVATIVE MITSUI TOATSU CHEM INC 1980-12-02 JP disclosed
US-4220468-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1980-09-02 US disclosed
JP-S5594353-A PHENOXYPHENYL CARBAMATE DERIVATIVE MITSUI TOATSU CHEM INC 1980-07-17 JP disclosed
US-4185995-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1980-01-29 US disclosed
US-4093446-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed
US-4070178-A Herbicidal diphenyl ethers ROHM AND HAAS COMPANY (US) 1978-01-24 US disclosed
US-4063929-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1977-12-20 US disclosed
US-4046798-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1977-09-06 US disclosed