SCHEMBL11090445

SCHEMBL11090445

Oc1cccc(Oc2ccc(C(F)(F)F)cc2Br)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
ATM Q13315 1/20 0.49
RAB9A P51151 3/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
MAPT P10636 3/20 0.48
EPAS1 Q99814 2/20 0.46
THRB P10828 3/20 0.44
THRA P10827 2/20 0.44
PPARG P37231 2/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
STK39 Q9UEW8 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9572372 0.84 NPSR1 (0.49) NPSR1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL11366475 0.83 L3MBTL1 (0.48) NPSR1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL8749364 0.82 RAB9A (0.61) NPSR1RAB9AL3MBTL1MAPTSTK39
SCHEMBL11091487 0.80 MAPK1 (0.57) CYP3A4ATML3MBTL1MAPTTHRB
SCHEMBL6229502 0.79 RAB9A (0.56) NPSR1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL11094525 0.79 SCN9A (0.51) NPSR1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL9827905 0.78 RAB9A (0.55) RAB9AMAPTLMNAMEN1NPC1
SCHEMBL9589388 0.78 RAB9A (0.55) NPSR1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL875278 0.77 EPAS1 (0.55) NPSR1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL27381706 0.77 ACHE (0.46) CYP1A2CYP2C19CYP3A4CYP2D6RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4443248-A Phenoxyphenoxypropionic acids and derivatives, and their use as herbicides VELSICOL CHEMICAL CORPORATION (US) 1984-04-17 US disclosed