Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875801 | 0.91 | DGKA (0.52) | DGKAALDH1A1TDP1DNM1TSHR | |
| SCHEMBL9951891 | 0.86 | DGKA (0.59) | DGKAALDH1A1TDP1DNM1TSHR | |
| SCHEMBL22615105 | 0.85 | DGKA (0.62) | DGKAALDH1A1TDP1DNM1TSHR | |
| SCHEMBL22615111 | 0.85 | DGKA (0.62) | DGKAALDH1A1TDP1DNM1TSHR | |
| SCHEMBL22615113 | 0.85 | DGKA (0.62) | DGKAALDH1A1TDP1DNM1TSHR | |
| SCHEMBL4418157 | 0.85 | ADRA2A (0.41) | DGKAALDH1A1TDP1MAPT | |
| SCHEMBL29293359 | 0.84 | DGKA (0.47) | DGKAALDH1A1TDP1DNM1TSHR | |
| Ethylene Glycol Dipentanoate SCHEMBL812973 | 0.82 | DGKA (0.82) | DGKAALDH1A1TDP1DNM1TSHR | |
| SCHEMBL3330237 | 0.82 | NAAA (0.44) | DGKAALDH1A1TDP1DNM1NAAA | |
| SCHEMBL28518046 | 0.81 | DGKA (0.42) | DGKAALDH1A1TDP1DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037665-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER FOR TREATMENT OF PULMONARY HYPERTENSION AND OTHER RESPIRATORY CONDITIONS | ORAL DELIVERY TECHNOLOGY LTD. (CA) | 2012-03-29 | — | — | WO | disclosed |