SCHEMBL9951891

SCHEMBL9951891

CCCCCC(=O)OCCCO[N+](=O)[O-]

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.59
DNM1 Q05193 1/20 0.50
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
TSHR P16473 1/20 0.47
PAM P19021 2/20 0.46
ALDH1A1 P00352 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
NAAA Q02083 1/20 0.46
HTR2C P28335 1/20 0.45
MAPT P10636 1/20 0.44
EPHX2 P34913 1/20 0.43
LMNA P02545 1/20 0.42
P2RY10 O00398 3/20 0.42
GPR34 Q9UPC5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22615111 0.98 DGKA (0.62) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL22615105 0.98 DGKA (0.62) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL22615113 0.98 DGKA (0.62) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL875801 0.92 DGKA (0.52) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL22615109 0.90 MGLL (0.53) DGKAALDH1A1MAPTEPHX2P2RY10
SCHEMBL10063280 0.90 CA12 (0.44) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL4531144 0.88 DGKA (0.50) DGKATSHRALDH1A1MAPTEPHX2
SCHEMBL4361944 0.88 DGKA (0.50) DGKATSHRALDH1A1MAPTEPHX2
SCHEMBL874973 0.86 DGKA (0.58) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL3330237 0.86 NAAA (0.44) DGKADNM1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634138-A1 NEW METHOD FOR SUSTAINABLE MANURE MANAGEMENT DSM IP Assets B.V. (NL) 2025-10-22 EP claimed
WO-2024126430-A1 NEW METHOD FOR SUSTAINABLE MANURE MANAGEMENT DSM IP ASSETS B.V. (NL) 2024-06-20 WO claimed
US-10154981-B2 Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2018-12-18 US claimed
EP-2654455-B1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS DSM IP ASSETS BV (NL) 2018-10-24 EP claimed
EP-3041365-B1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RU-MINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2018-04-04 EP claimed
US-9902685-B2 Use of nitrooxy organic molecules in feed for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2018-02-27 US claimed
EP-3238720-A1 ANTI-METHANOGENIC COMPOSITIONS AND USES THEREOF DSM IP Assets B.V. (NL) 2017-11-01 EP claimed
WO-2017137489-A1 ANTI-METHANOGENIC COMPOSITIONS AND USES THEREOF DSM IP ASSETS B.V. (NL) 2017-08-17 WO claimed
US-20160183564-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2016-06-30 US claimed
CN-103561586-B Fodder compound is for reducing the discharge of methane of ruminant and/or improving the purposes that ruminant shows DSM IP ASSETS B.V. (NL) 2016-05-04 CN claimed
US-9266814-B2 Use of nitrooxy organic molecules in feed for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2016-02-23 US claimed
US-20150376113-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2015-12-31 US claimed
US-20140147529-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2014-05-29 US claimed
EP-2654455-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP Assets B.V. (NL) 2013-10-30 EP claimed
WO-2012084629-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2012-06-28 WO claimed
EP-4634138-A1 NEW METHOD FOR SUSTAINABLE MANURE MANAGEMENT DSM IP Assets B.V. (NL) 2025-10-22 EP disclosed
WO-2025151713-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO disclosed
WO-2012160191-A2 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2012-11-29 WO disclosed
WO-2012084629-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2012-06-28 WO disclosed
WO-2012084629-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2012-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10154981-B2 Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance OAT, MRM1, ETFA DGKA 4032/4885DNM1 722/4885PRSS1 2697/4885
US-20140147529-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE MLNR, PIGS, MTR DGKA 4605/4885DNM1 895/4885PRSS1 2306/4885
US-20150376113-A1 USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE MLNR, PIGS, MTR DGKA 4605/4885DNM1 895/4885PRSS1 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.