Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 11/20 | 0.53 |
| ▸ | CTSS | P25774 | 7/20 | 0.53 |
| ▸ | CTSL | P07711 | 6/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470479 | 0.90 | PPARA (0.67) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL6436359 | 0.88 | CTSK (0.60) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL15354873 | 0.86 | PPARA (0.61) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL376154 | 0.85 | SYK (0.57) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL995705 | 0.85 | SYK (0.57) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL2619553 | 0.85 | SYK (0.57) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL6320951 | 0.85 | SYK (0.59) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL4641124 | 0.85 | SYK (0.59) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL2677162 | 0.85 | SYK (0.59) | PPARASYKCTSKCTSSCTSL | |
| SCHEMBL13640158 | 0.84 | PPARA (0.59) | PPARASYKCTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482080-B1 | SMALL CYCLIC PLATELET AGGREGATION INHIBITORS | GENENTECH INC (US) | 1997-03-26 | — | — | EP | disclosed |