Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTPRG | P23470 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.32 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813541 | 0.75 | CRBN (0.33) | CRBNMAPT | |
| SCHEMBL8749795 | 0.74 | KMT2A (0.40) | CRBNKDM4EPTPRGKMT2AMEN1 | |
| SCHEMBL8433852 | 0.73 | PTPRG (0.58) | KDM4EPTPRGKMT2AMEN1LMNA | |
| SCHEMBL8749837 | 0.72 | CYP2C19 (0.32) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1068302 | 0.66 | GAA (0.48) | CRBNKMT2AMEN1LMNADDB1 | |
| Ammonia Solution, Strong SCHEMBL9774304 | 0.65 | GAA (0.47) | CRBNKMT2AMEN1LMNADDB1 | |
| SCHEMBL1887461 | 0.65 | TLR9 (0.45) | CRBNKDM4EKMT2AMEN1MAPT | |
| SCHEMBL28411469 | 0.62 | GLA (0.56) | CRBNKMT2ALMNAMAPTHTT | |
| SCHEMBL309593 | 0.61 | MAP3K14 (0.35) | CRBNKMT2AMEN1L3MBTL1DDB1 | |
| SCHEMBL30363164 | 0.61 | ALDH1A1 (0.39) | KDM4ELMNAMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496473-B1 | Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-03-26 | — | — | EP | claimed |
| EP-0496472-B1 | Succinimide containing polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-11-29 | — | — | EP | claimed |
| US-5308749-A | REACTING A WATER INSOLUBLE, NONPOROUS PARTICLE OF A NONCROSSLINKED COPOLYMER WITH A BIOLOGICALLY ACTIVE SUBSTANCE | EASTMAN KODAK COMPANY (US) | 1994-05-03 | — | — | US | claimed |
| US-5200462-A | Water-insoluble, noncrosslinked, nonporous; diagnostic assays | EASTMAN KODAK COMPANY (US) | 1993-04-06 | — | — | US | claimed |
| EP-0496472-A1 | Succinimide containing polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-07-29 | — | — | EP | claimed |
| EP-0496473-A2 | Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-07-29 | — | — | EP | claimed |
| EP-0496473-B1 | Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0496472-B1 | Succinimide containing polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5308749-A | REACTING A WATER INSOLUBLE, NONPOROUS PARTICLE OF A NONCROSSLINKED COPOLYMER WITH A BIOLOGICALLY ACTIVE SUBSTANCE | EASTMAN KODAK COMPANY (US) | 1994-05-03 | — | — | US | disclosed |
| US-5200462-A | Water-insoluble, noncrosslinked, nonporous; diagnostic assays | EASTMAN KODAK COMPANY (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0496472-A1 | Succinimide containing polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0496473-A2 | Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-07-29 | — | — | EP | disclosed |