SCHEMBL3813541

SCHEMBL3813541

C=Cc1ccc(CSCCC(=O)OC2CC(=O)NC2=O)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.33
CYP2C19 P33261 1/20 0.32
HPGD P15428 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749837 0.79 CYP2C19 (0.32) CYP2C19
SCHEMBL8749783 0.75 CRBN (0.41) CRBNMAPT
SCHEMBL977159 0.72 MAP3K14 (0.38) CRBNMAPT
SCHEMBL17941727 0.72 NLRP3 (0.39)
SCHEMBL3813545 0.71 CYP2C19 (0.35) CYP2C19HPGDMAPT
SCHEMBL5674593 0.70 CYP2C19 (0.64) CYP2C19HPGD
SCHEMBL20589363 0.68 PRKCA (0.38) MAPT
SCHEMBL6551912 0.67 HSD17B10 (0.39)
SCHEMBL8436879 0.67 CYP2C19 (0.44) CYP2C19HPGD
SCHEMBL10488014 0.67 MAP3K14 (0.35) CRBNMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009118492-A1 RANDOM ETHYLENE POLYMER INCLUDING A REACTION GROUP AND A SILICONIZED GROUP, COSMETIC COMPOSITION AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-10-01 WO claimed
WO-2009106781-A2 COSMETIC COMPOSITION CONTAINING A RANDOM ETHYLENIC POLYMER CONTAINING A REACTIVE GROUP AND AN IONISABLE GROUP, COSMETIC TREATMENT METHOD AND NOVEL POLYMERS L'OREAL (FR) 2009-09-03 WO claimed
WO-2009106782-A2 COSMETIC COMPOSITION CONTAINING A RANDOM ETHYLENIC POLYMER WITH A REACTIVE GROUP, AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-09-03 WO claimed
EP-0496473-B1 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1997-03-26 EP claimed
EP-0496472-B1 Succinimide containing polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1995-11-29 EP claimed
US-5308749-A REACTING A WATER INSOLUBLE, NONPOROUS PARTICLE OF A NONCROSSLINKED COPOLYMER WITH A BIOLOGICALLY ACTIVE SUBSTANCE EASTMAN KODAK COMPANY (US) 1994-05-03 US claimed
US-5200462-A Water-insoluble, noncrosslinked, nonporous; diagnostic assays EASTMAN KODAK COMPANY (US) 1993-04-06 US claimed
EP-0496472-A1 Succinimide containing polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-07-29 EP claimed
EP-0496473-A2 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-07-29 EP claimed
WO-2009118492-A1 RANDOM ETHYLENE POLYMER INCLUDING A REACTION GROUP AND A SILICONIZED GROUP, COSMETIC COMPOSITION AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-10-01 WO disclosed
WO-2009106782-A2 COSMETIC COMPOSITION CONTAINING A RANDOM ETHYLENIC POLYMER WITH A REACTIVE GROUP, AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-09-03 WO disclosed
WO-2009106781-A2 COSMETIC COMPOSITION CONTAINING A RANDOM ETHYLENIC POLYMER CONTAINING A REACTIVE GROUP AND AN IONISABLE GROUP, COSMETIC TREATMENT METHOD AND NOVEL POLYMERS L'OREAL (FR) 2009-09-03 WO disclosed
EP-0496473-B1 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1997-03-26 EP disclosed
EP-0496472-B1 Succinimide containing polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1995-11-29 EP disclosed
US-5308749-A REACTING A WATER INSOLUBLE, NONPOROUS PARTICLE OF A NONCROSSLINKED COPOLYMER WITH A BIOLOGICALLY ACTIVE SUBSTANCE EASTMAN KODAK COMPANY (US) 1994-05-03 US disclosed
US-5200462-A Water-insoluble, noncrosslinked, nonporous; diagnostic assays EASTMAN KODAK COMPANY (US) 1993-04-06 US disclosed
EP-0496472-A1 Succinimide containing polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-07-29 EP disclosed
EP-0496473-A2 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-07-29 EP disclosed