SCHEMBL1887461

SCHEMBL1887461

O=C1CC(OC(=O)c2ccccc2N2C(=O)C=CC2=O)C(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HSP90AA1 P07900 2/20 0.45
ATM Q13315 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
PKM P14618 1/20 0.45
CCR6 P51684 1/20 0.45
DDB1 Q16531 2/20 0.39
CRBN Q96SW2 2/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
MGLL Q99685 8/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
MITF O75030 1/20 0.34
HTT P42858 1/20 0.34
MAPT P10636 2/20 0.33
HSD17B10 Q99714 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1061152 0.78 ALDH1A1 (0.48) TLR9ALDH1A1HSP90AA1ATMNPSR1
SCHEMBL5956001 0.76 MGLL (0.42) ALDH1A1HSP90AA1ATMPKMMEN1
SCHEMBL1068302 0.74 GAA (0.48) ALDH1A1DDB1CRBNMEN1KMT2A
SCHEMBL617412 0.73 RAB9A (0.42) ALDH1A1PKMDDB1CRBNMEN1
Ammonia Solution, Strong SCHEMBL9774304 0.73 GAA (0.47) ALDH1A1DDB1CRBNMEN1KMT2A
SCHEMBL5320949 0.72 HTT (0.42) ALDH1A1DDB1CRBNPOLBSMN1; SMN2
SCHEMBL660307 0.71 GAA (0.43) ALDH1A1PKMDDB1CRBNMEN1
SCHEMBL28472385 0.70 TLR9 (0.58) TLR9ALDH1A1HSP90AA1ATMNPSR1
SCHEMBL11357026 0.69 TDP1 (0.57) TLR9ALDH1A1HSP90AA1ATMNPSR1
SCHEMBL28436940 0.69 CRBN (0.56) ALDH1A1TDP1DDB1CRBNMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6321998-A None JP disclosed
EP-4722227-A1 COMPLEX, PHARMACEUTICAL COMPOSITION, VACCINE, AND APPLICATIONS THEREOF ENU Pharma, Inc. (JP) 2026-04-08 EP disclosed
US-12559522-B2 Cell penetrating peptide ASTELLAS PHARMA INC. (JP) 2026-02-24 US disclosed
WO-2024241964-A1 COMPLEX, PHARMACEUTICAL COMPOSITION, VACCINE, AND APPLICATIONS THEREOF 遠友ファーマ株式会社 2024-11-28 WO disclosed
US-20240317804-A1 CELL PENETRATING PEPTIDE ASTELLAS PHARMA INC. (JP) 2024-09-26 US disclosed
US-12018095-B2 Cell penetrating peptide ASTELLAS PHARMA INC. (JP) 2024-06-25 US disclosed
US-11712466-B2 Vaccine composition TOHOKU UNIVERSITY (JP) 2023-08-01 US disclosed
US-20220356207-A1 CELL PENETRATING PEPTIDE ASTELLAS PHARMA INC. (JP) 2022-11-10 US disclosed
US-11414456-B2 Cell penetrating peptide ASTELLAS PHARMA INC. (JP) 2022-08-16 US disclosed
US-20210163533-A1 CELL PENETRATING PEPTIDE ASTELLAS PHARMA INC. (JP) 2021-06-03 US disclosed
EP-2484698-A1 HYBRIDOMA PRODUCING ANTI-METHYLATED DNA ANTIBODY AND UTILIZATION OF SAME Sysmex Corporation (JP) 2012-08-08 EP disclosed
US-20120184719-A1 HYBRIDOMA PRODUCING ANTI-METHYLATED DNA ANTIBODY AND UTILIZATION OF SAME SYSMEX CORPORATION (JP) 2012-07-19 US disclosed
US-20110111427-A1 BIOMARKER FOR THE ESTIMATION OF ACUTE RENAL DISORDER AND PROGNOSIS OF THE DISORDER, AND USE OF THE BIOMARKER NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2011-05-12 US disclosed
EP-2261660-A1 BIOMARKER FOR THE ESTIMATION OF ACUTE RENAL DISORDER AND PROGNOSIS OF THE DISORDER, AND USE OF THE BIOMARKER National University Corporation Nagoya University (JP) 2010-12-15 EP disclosed
US-20090203538-A1 Method of classifying antibody, method of identifying antigen, method of obtaining antibody or antibody set, method of constructing antibody panel and antibody or antibody set and use of the same INSTITUTE FOR ANTIBODIES CO., LTD. (JP) 2009-08-13 US disclosed
EP-2078732-A1 METHOD OF CLASSIFYING ANTIGEN, METHOD OF IDENTIFYING ANTIGEN, METHOD OF OBTAINING ANTIBODY OR ANTIBODY SET, METHOD OF CONSTRUCTING ANTIBODY PANEL AND ANTIBODY OR ANTIBODY SET AND USE OF THE SAME Institute for Antibodies Co., Ltd. (JP) 2009-07-15 EP disclosed
US-20070081974-A1 Antibody targeting osteoclast-associated protein SANKYO COMPANY, LIMITED (JP) 2007-04-12 US disclosed
US-20070031421-A1 Inhibitors targeting osteoclast-associated protein SANKYO COMPANY, LIMITED (JP) 2007-02-08 US disclosed
EP-1715038-A1 ANTIBODY TARGETING OSTEOCLAST-ASSOCIATED PROTEIN Sankyo Company, Limited (JP) 2006-10-25 EP disclosed
JP-H06321998-A ANTI-FUMONISIN MONOCLONAL ANTIBODY, HYBRIDOMA, HAPTEN ANTIGEN AND THEIR PRODUCTION KIKKOMAN CORP 1994-11-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184719-A1 HYBRIDOMA PRODUCING ANTI-METHYLATED DNA ANTIBODY AND UTILIZATION OF SAME DNMT1, DNMT3A, MPG TLR9 205/4885ALDH1A1 3217/4885HSP90AA1 3076/4885
US-12559522-B2 Cell penetrating peptide SLC29A1, SLC29A2, DCX TLR9 1914/4885ALDH1A1 4864/4885HSP90AA1 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.