Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750157 | 0.85 | CTRC (0.48) | PON1CTRCCA12ALDH1A1KDM4E | |
| SCHEMBL8750126 | 0.82 | KDM4E (0.47) | PON1CA12ALDH1A1KDM4EHPGD | |
| SCHEMBL26346444 | 0.73 | ERN1 (0.44) | PON1CA12ALDH1A1KDM4EHPGD | |
| SCHEMBL8750130 | 0.72 | CA12 (0.60) | CTRCCA12ALDH1A1KDM4EHPGD | |
| SCHEMBL8750124 | 0.70 | CTRC (0.48) | CTRCCA12ALDH1A1KDM4EHPGD | |
| SCHEMBL8750120 | 0.70 | CA12 (0.50) | CA12ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL13836162 | 0.70 | ALDH1A1 (0.55) | PON1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL8750110 | 0.69 | CYP2A6 (0.45) | CTRCALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3362853 | 0.68 | MAOB (0.59) | CA12ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL15842585 | 0.68 | CA12 (0.60) | CTRCCA12ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | claimed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | claimed |
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |