SCHEMBL8750285

SCHEMBL8750285

C=CCOC(=O)OC1CC(=O)N(CC=C)C1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP3A4 P08684 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750297 0.84 BRD4 (0.33) HSD17B10MAPTMAPK1MEN1USP2
SCHEMBL692642 0.82 HSD17B10 (0.37) HSD17B10MAPTMAPK1MEN1USP2
SCHEMBL8750280 0.82 BRD4 (0.39) KCNA3NPSR1CYP3A4GAA
SCHEMBL11522239 0.75 MEN1 (0.43) HSD17B10MAPTMEN1USP2TSHR
SCHEMBL5599867 0.71 KCNA3 (0.42) KCNA3HSD17B10MAPTMAPK1TSHR
SCHEMBL10628769 0.69 APEX1 (0.53) HSD17B10MAPTMAPK1MEN1USP2
SCHEMBL14145905 0.68 HSD17B10 (0.36) HSD17B10MAPTMEN1USP2TSHR
SCHEMBL692641 0.68 POLB (0.57) HSD17B10MAPTMAPK1GAA
SCHEMBL8271284 0.68 POLB (0.57) HSD17B10MAPTMAPK1GAA
SCHEMBL2329949 0.68 ALDH1A1 (0.37) KCNA3HSD17B10MAPTTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601321-B1 Binders composition for electrodeposition BASF LACKE & FARBEN (DE) 1997-02-19 EP disclosed
EP-0601321-A1 Binders composition for electrodeposition BASF Lacke + Farben AG (DE) 1994-06-15 EP disclosed