SCHEMBL8750574

SCHEMBL8750574

Cc1ccc(C(C)OC(C)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
TRPA1 O75762 1/20 0.40
PTGS1 P23219 1/20 0.40
CACNA1C Q13936 1/20 0.40
TDP1 Q9NUW8 3/20 0.38
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.36
CHRNA7 P36544 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 2/20 0.32
RECQL P46063 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9070269 0.84 SMN1; SMN2 (0.37) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL267746 0.84 LMNA (0.40) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL24589242 0.80 TDP1 (0.46) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL12051708 0.79 LMNA (0.36) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL20718662 0.78 LMNA (0.43) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL29352459 0.77 LMNA (0.46) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL30475871 0.77 LMNA (0.46) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL598134 0.77 LMNA (0.65) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL2336888 0.77 LMNA (0.46) LMNATRPA1PTGS1CACNA1CTDP1
SCHEMBL18361379 0.77 LMNA (0.35) LMNATRPA1PTGS1CACNA1CTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523697-B1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS (JP) 1997-04-02 EP disclosed
EP-0268878-B1 Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents MITSUI TOATSU CHEMICALS (JP) 1996-01-31 EP disclosed
US-5447901-A Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid MITSUI TOATSU CHEMICAL, INC. (JP) 1995-09-05 US disclosed
US-5376615-A Pressure sensitive elements containing a salicylic acid resin and a phenolic resin MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-12-27 US disclosed
EP-0523697-A1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed
US-5023366-A Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-06-11 US disclosed
EP-0268878-A2 Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-01 EP disclosed