SCHEMBL598134

SCHEMBL598134

Cc1ccc(C(C)C)cc1C

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.65
PTGS1 P23219 2/20 0.62
TRPA1 O75762 1/20 0.62
CACNA1C Q13936 1/20 0.62
ALDH1A1 P00352 3/20 0.43
HTT P42858 2/20 0.43
GAA P10253 1/20 0.43
ALOX12 P18054 1/20 0.43
HIF1A Q16665 1/20 0.43
PTGS2 P35354 1/20 0.41
ACHE P22303 4/20 0.41
BCHE P06276 3/20 0.41
RNASEH1 O60930 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TYR P14679 1/20 0.39
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31051327 0.83 LMNA (0.90) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL29352459 0.83 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL2336888 0.83 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL30475871 0.83 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL10416092 0.82 LMNA (0.86) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL8161309 0.82 LMNA (0.47) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL20676163 0.81 LMNA (0.77) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL16646918 0.81 LMNA (0.44) LMNAPTGS1TRPA1CACNA1CALDH1A1
Anisole SCHEMBL6287292 0.80 CA4 (0.50) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL18482830 0.79 LMNA (0.43) LMNAPTGS1TRPA1CACNA1CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564979-B1 Method for the production of dixylylpropane HOECHST AG (DE) 1996-08-28 EP claimed
US-5300717-A Reacting o-xylene with propene; Friedel-Crafts catalyst; dehydrogenation. chlorination, condensation; intermediate for bisanhydride precursor for polyimides HOECHST AKTIENGESELLSCHAFT (DE) 1994-04-05 US claimed
EP-0564979-A2 Method for the production of dixylylpropane HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-13 EP claimed
US-4163863-A PEROXIDATION OF AN ALKYLBENZENE, ACID CATALYZED DECOMPOSITION OF PEROXIDE, CATALYTIC HYDROGENATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-08-07 US claimed
JP-6048966-A None JP disclosed
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS Kinoxis Therapeutics Pty Ltd (AU) 2024-02-29 US disclosed
US-11759458-B2 Indane-amines as PD-L1 antagonists CHEMOCENTRYX, INC. (US) 2023-09-19 US disclosed
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-06 US disclosed
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS KITTRICH CORPORATION 2023-06-22 US disclosed
EP-3360175-B1 FORMULATIONS COMPRISING AT LEAST TWO ORGANIC SEMICONDUCTING COMPOUNDS AND AT LEAST TWO SOLVENTS MERCK PATENT GMBH (DE) 2023-05-17 EP disclosed
CN-111039800-B Organic compound containing condensed ring structure and organic electroluminescent device 北京绿人科技有限责任公司 2022-11-04 CN disclosed
WO-2021069331-A1 LILY OF THE VALLEY ODORANT FIRMENICH SA (CH) 2021-04-15 WO disclosed
EP-0077749-A1 Process for preparing a methyl phenol THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-04-27 EP disclosed
EP-0018803-B1 PROCESS FOR PREPARATION OF AROMATIC TERTIARY HYDROPEROXIDES AND PHENOLS PREPARED THEREFROM MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-05-12 EP disclosed
US-4288637-A COPPER PEROXIDATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-09-08 US disclosed
EP-0018803-A1 Process for preparation of aromatic tertiary hydroperoxides and phenols prepared therefrom MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1980-11-12 EP disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
EP-0012514-A1 Alkylation of aromatic hydrocarbons MOBIL OIL CORPORATION (US) 1980-06-25 EP disclosed
US-4163863-A PEROXIDATION OF AN ALKYLBENZENE, ACID CATALYZED DECOMPOSITION OF PEROXIDE, CATALYTIC HYDROGENATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-08-07 US disclosed
US-4108907-A Process for the preparation of polyalkylbenzene hydroperoxides KOPPERS COMPANY, INC. (US) 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS CYP51A1, CYP4A22, ACHE LMNA 2776/4885PTGS1 346/4885TRPA1 325/4885
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OTC, OCIAD1 LMNA 1825/4885PTGS1 2867/4885TRPA1 132/4885
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS OXTR, AVPR1B, AVPR1A LMNA 2876/4885PTGS1 325/4885TRPA1 220/4885
US-11759458-B2 Indane-amines as PD-L1 antagonists CD274, PDCD1LG2, PDCD1 LMNA 1696/4885PTGS1 2028/4885TRPA1 2131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.