Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750574 | 0.84 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CTDP1 | |
| SCHEMBL12062531 | 0.81 | SLC6A2 (0.43) | ALDH1A1AKR1C2TAS1R3TAS1R1HPGD | |
| SCHEMBL26938093 | 0.81 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CAKR1C2 | |
| SCHEMBL8282434 | 0.81 | AKR1C2 (0.43) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL23050335 | 0.81 | CYP3A4 (0.45) | LMNATDP1ALDH1A1AKR1C2AKR1C1 | |
| SCHEMBL24589210 | 0.81 | TDP1 (0.45) | LMNATRPA1PTGS1CACNA1CTDP1 | |
| SCHEMBL8251349 | 0.81 | CYP11B1 (0.37) | LMNAAKR1C2AKR1C1TSHRCYP11B1 | |
| SCHEMBL6846328 | 0.79 | ALDH1A1 (0.37) | LMNATRPA1PTGS1CACNA1CTDP1 | |
| SCHEMBL1338710 | 0.77 | AKR1C2 (0.42) | TDP1ALDH1A1AKR1C2AKR1C1TSHR | |
| SCHEMBL12051708 | 0.77 | LMNA (0.36) | LMNATRPA1PTGS1CACNA1CTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133869-B2 | And oxidized natural lignin phenols with a low molecular weigh; disinfecting, microbicidal, root growth enhancing activity | Lopretti, Mary (UY) | 2012-03-13 | — | — | US | disclosed |
| US-8076364-B2 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20110092506-A1 | TRISUBSTITUTED AMINE COMPOUND | NAKAMURA YOSHINORI | 2011-04-21 | — | — | US | disclosed |
| US-20080220974-A1 | COMPOSITIONS CONTAINING POLY[BETA(1,4)-2-AMINO-2-DEOXYGLUCOPYRANOSE] OLIGOMERS IN A SOLUTION OF MODIFIED LIGNIN PHENOLS AND THEIR USES | LOPRETTI MARY | 2008-09-11 | — | — | US | disclosed |
| EP-0268878-B1 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5447901-A | Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid | MITSUI TOATSU CHEMICAL, INC. (JP) | 1995-09-05 | — | — | US | disclosed |
| US-5376615-A | Pressure sensitive elements containing a salicylic acid resin and a phenolic resin | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-12-27 | — | — | US | disclosed |
| US-5023366-A | Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0268878-A2 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092506-A1 | TRISUBSTITUTED AMINE COMPOUND | CETP, MTTP, APOB | LMNA 1103/4885TRPA1 4332/4885PTGS1 2962/4885 |
| US-20080220974-A1 | COMPOSITIONS CONTAINING POLY[BETA(1,4)-2-AMINO-2-DEOXYGLUCOPYRANOSE] OLIGOMERS IN A SOLUTION OF MODIFIED LIGNIN PHENOLS AND THEIR USES | PGLS, PLOD1, DAO | LMNA 2159/4885TRPA1 1380/4885PTGS1 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.