Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.59 |
| ▸ | PDE4A | P27815 | 5/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TPO | P07202 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360066 | 0.82 | ADORA2B (0.75) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL985620 | 0.77 | ADORA2B (0.63) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL31060278 | 0.75 | ADORA2B (1.00) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL9750957 | 0.74 | ADORA2B (0.69) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL7326382 | 0.71 | PDE4A (0.68) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL4014471 | 0.71 | ADORA2A (0.63) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL4602969 | 0.71 | ADORA2B (0.73) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL5677075 | 0.71 | ADORA2B (0.62) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL13735421 | 0.70 | ADORA2B (0.55) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL5515444 | 0.70 | ADORA2A (0.71) | ADORA2BADORA3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764647-A1 | Substituted xanthins | BAYER AG (DE) | 1997-03-26 | — | — | EP | disclosed |