Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.63 |
| ▸ | PDE4A | P27815 | 6/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326382 | 0.85 | PDE4A (0.68) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7326960 | 0.81 | ADORA2A (0.67) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL60158 | 0.80 | ADORA2A (0.70) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27396492 | 0.78 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL380135 | 0.78 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL59949 | 0.78 | ADORA2B (0.72) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7217322 | 0.77 | ADORA2A (0.97) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL985620 | 0.76 | ADORA2B (0.63) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4602969 | 0.76 | ADORA2B (0.73) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4423680 | 0.76 | ADORA2B (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114146229-A | Preparation method of nanofiber scaffold and method for constructing tissue engineering material by adopting nanofiber scaffold and melanocytes | 上海麦野生物科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| US-20090148546-A1 | Methods and compounds fo rthe treatment of obesity and obesity-related disorders | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2009-06-11 | — | — | US | disclosed |
| US-7479540-B1 | Adipomodulin and related molecules and methods | PRASAD CHANDAN | 2009-01-20 | — | — | US | disclosed |
| WO-2006086764-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS | THE BOARD OF SUPERVISOR OF LOUISIANA STATE UNIVERSITY AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20060182825-A1 | Methods and compounds for the treatment of obesity and obesity-related disorders | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2006-08-17 | — | — | US | disclosed |