Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17636899 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL812723 | 0.75 | GABRA1 (0.52) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL6180997 | 0.73 | GABRA1 (0.50) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL3206761 | 0.71 | GABRA1 (0.48) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL8159500 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL28914676 | 0.71 | GABRA1 (0.48) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL3116485 | 0.71 | GABRA1 (0.48) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL10037121 | 0.71 | GABRA1 (0.48) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL22767461 | 0.71 | GABRA1 (0.54) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 | |
| SCHEMBL8750954 | 0.71 | LMNA (0.48) | SMN1; SMN2GABRA1LMNAGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710257-B1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL CO (US) | 1997-04-02 | — | — | EP | claimed |
| EP-0710257-A1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL CO (US) | 1996-05-08 | — | — | EP | claimed |
| US-5405924-A | Imido transition metal complex metathesis catalysts | SHELL OIL COMPANY (US) | 1995-04-11 | — | — | US | claimed |
| WO-1995003346-A1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL COMPANY (US) | 1995-02-02 | — | — | WO | claimed |
| EP-0710257-B1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL CO (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0710257-A1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL CO (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5405924-A | Imido transition metal complex metathesis catalysts | SHELL OIL COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| WO-1995003346-A1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL COMPANY (US) | 1995-02-02 | — | — | WO | disclosed |