Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27839904 | 0.97 | GABRA1 (0.48) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL5082721 | 0.86 | MAPK1 (0.47) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL11661792 | 0.84 | LMNA (0.41) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL11661447 | 0.84 | SMN1; SMN2 (0.44) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| Hydrochloric Acid SCHEMBL2866658 | 0.84 | MAPK1 (0.46) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL812723 | 0.81 | GABRA1 (0.52) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL23562240 | 0.81 | SMN1; SMN2 (0.46) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL14200015 | 0.81 | LPAR1 (0.53) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL25658362 | 0.80 | GABRA1 (0.38) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| Hydrochloric Acid SCHEMBL27820465 | 0.78 | LMNA (0.34) | GABRA1LMNAGABRG2GABRB3GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369689-A1 | Arylaminosilane Compound, Propylene Polymerization Catalyst And Preparation Thereof | PETROCHINA COMPANY LIMITED (CN) | 2020-11-26 | — | — | US | claimed |
| CN-111978346-A | Arylamine silane compound, propylene polymerization catalyst, preparation and application thereof | 中国石油天然气股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| US-11744142-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-29 | — | — | US | disclosed |
| US-11700765-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-07-11 | — | — | US | disclosed |
| US-11535638-B2 | Arylaminosilane compound, propylene polymerization catalyst and preparation thereof | PETROCHINA COMPANY LIMITED (CN) | 2022-12-27 | — | — | US | disclosed |
| US-20220162160-A1 | SOLID DRUG FORM OF N-(2,6-BIS(1-METHYLETHYL)PHENYL)-N'-((1-(4-(DIMETHYLAMINO)PHENYL)CYCLOPENTYL)METHYL)UREA HYDROCHLORIDE AND COMPOSITIONS, METHODS AND KITS RELATED THERETO | MILLENDO THERAPEUTICS, INC. | 2022-05-26 | — | — | US | disclosed |
| EP-3190889-B1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME (US) | 2021-11-17 | — | — | EP | disclosed |
| US-20210351356-A1 | IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES | Konica Minolta, Inc. (JP) | 2021-11-11 | — | — | US | disclosed |
| US-20200369689-A1 | Arylaminosilane Compound, Propylene Polymerization Catalyst And Preparation Thereof | PETROCHINA COMPANY LIMITED (CN) | 2020-11-26 | — | — | US | disclosed |
| CN-111978346-A | Arylamine silane compound, propylene polymerization catalyst, preparation and application thereof | 中国石油天然气股份有限公司 | 2020-11-24 | — | — | CN | disclosed |
| US-20200295281-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-09-17 | — | — | US | disclosed |
| US-20120022070-A1 | Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use | EMORY UNIVERSITY (US) | 2012-01-26 | — | — | US | disclosed |
| CN-102161682-A | Non-bridged N-substituted aryllamino mono-titanocene compound and application thereof | UNIV JILIN | 2011-08-24 | — | — | CN | disclosed |
| EP-0920424-B1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1238996-B1 | NORBORNENE OPEN-RING POLYMERS, PRODUCTS OF HYDROGENATION THEREOF AND PROCESSES FOR THE PRODUCTION OF BOTH | ZEON CORP (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6653424-B1 | Using polymerization catalyst comprising transition metal imide of Group 6 substituted by alkyloxy, aryloxy, alkylamide and/or arylamide groups; high melting | ZEON CORPORATION (JP) | 2003-11-25 | — | — | US | disclosed |
| EP-1238996-A1 | NORBORNENE OPEN-RING POLYMERS, PRODUCTS OF HYDROGENATION THEREOF AND PROCESSES FOR THE PRODUCTION OF BOTH | Zeon Corporation (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-6251962-B1 | ACRYLATE POLYMER | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-06-26 | — | — | US | disclosed |
| US-6194437-B1 | ANTIDEPRESSANTS; ANTICANCER AGENTS; GASTROINTESTINAL DISORDERS; COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY | 2001-02-27 | — | — | US | disclosed |
| US-4101575-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200295281-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SOD1, L1CAM, MCM2 | GABRA1 3760/4885LMNA 1184/4885GABRG2 2574/4885 |
| US-11744142-B2 | Organic electroluminescent materials and devices | TLL1, TLL2, ALPL | GABRA1 3043/4885LMNA 1136/4885GABRG2 3698/4885 |
| US-11535638-B2 | Arylaminosilane compound, propylene polymerization catalyst and preparation thereof | RPS8, PARP8, PRMT8 | GABRA1 3277/4885LMNA 1477/4885GABRG2 3923/4885 |
| US-20220162160-A1 | SOLID DRUG FORM OF N-(2,6-BIS(1-METHYLETHYL)PHENYL)-N'-((1-(4-(DIMETHYLAMINO)PHENYL)CYCLOPENTYL)METHYL)UREA HYDROCHLORIDE AND COMPOSITIONS, METHODS AND KITS RELATED THERETO | ATR, BAP1, ATRIP | GABRA1 1296/4885LMNA 3482/4885GABRG2 1706/4885 |
| US-20200369689-A1 | Arylaminosilane Compound, Propylene Polymerization Catalyst And Preparation Thereof | RPS8, PARP8, PRMT8 | GABRA1 3277/4885LMNA 1477/4885GABRG2 3923/4885 |
| US-11700765-B2 | Organic electroluminescent materials and devices | SOD1, L1CAM, MCM2 | GABRA1 3760/4885LMNA 1184/4885GABRG2 2574/4885 |
| US-20210351356-A1 | IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES | IGF1R, IK, BMI1 | GABRA1 2494/4885LMNA 2139/4885GABRG2 2430/4885 |
| US-20120022070-A1 | Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use | HSP90AB1, HSP90AA1, HSP90AB2P | GABRA1 4096/4885LMNA 3338/4885GABRG2 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.