Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.61 |
| ▸ | CTSB | P07858 | 5/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750890 | 0.94 | CTSL (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10521651 | 0.88 | ALDH1A1 (0.51) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL29480462 | 0.86 | CTSL (0.66) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8750885 | 0.84 | CTSL (0.66) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL6440666 | 0.83 | CTSL (0.64) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL6440663 | 0.83 | CTSL (0.64) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7269522 | 0.83 | CTSL (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10795546 | 0.82 | CTSL (0.61) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL4007938 | 0.82 | CTSL (0.61) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7608557 | 0.82 | CTSL (0.61) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561303-B1 | Conjugates of phenylalanine-glycine with antitumor substances | KUREHA CHEMICAL IND CO LTD (JP) | 1997-02-26 | — | — | EP | disclosed |
| US-5470960-A | Antitumor agents | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5411964-A | Phenylalanine-glycine compounds having anti-tumor activity, process for preparation thereof, and pharmaceutical composition containing said compounds | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0561303-A2 | Conjugates of phenylalanine-glycine with antitumor substances | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |