Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.62 |
| ▸ | CTSS | P25774 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.62 |
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750936 | 0.94 | CTSL (0.61) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10861784 | 0.87 | ALDH1A1 (0.56) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL10607439 | 0.85 | CTSK (0.55) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL12952246 | 0.84 | CTSL (0.69) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8668091 | 0.83 | TACR1 (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7268361 | 0.83 | CTSL (0.65) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL19807564 | 0.82 | TACR1 (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10802556 | 0.82 | CTSL (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7268180 | 0.81 | TACR1 (0.64) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL9725868 | 0.81 | CTSL (0.60) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561303-B1 | Conjugates of phenylalanine-glycine with antitumor substances | KUREHA CHEMICAL IND CO LTD (JP) | 1997-02-26 | — | — | EP | disclosed |
| US-5470960-A | Antitumor agents | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5411964-A | Phenylalanine-glycine compounds having anti-tumor activity, process for preparation thereof, and pharmaceutical composition containing said compounds | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0561303-A2 | Conjugates of phenylalanine-glycine with antitumor substances | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |