Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751982 | 0.85 | NPC1 (0.31) | — | |
| SCHEMBL8752048 | 0.84 | MAPK1 (0.32) | L3MBTL1 | |
| SCHEMBL8751995 | 0.83 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL8752040 | 0.82 | MEN1 (0.34) | — | |
| SCHEMBL8752003 | 0.80 | ADORA3 (0.41) | L3MBTL1NUDT1 | |
| SCHEMBL8752080 | 0.80 | ALOX15 (0.31) | — | |
| SCHEMBL8752062 | 0.79 | HTT (0.39) | L3MBTL1 | |
| SCHEMBL5928189 | 0.76 | ALDH1A1 (0.33) | L3MBTL1 | |
| SCHEMBL8752023 | 0.76 | ALDH1A1 (0.41) | L3MBTL1 | |
| SCHEMBL8752006 | 0.76 | HDAC3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684011-A | Pyrimidine derivatives useful as nematicides | ZENECA LIMITED (GB) | 1997-11-04 | — | — | US | disclosed |
| EP-0660827-B1 | HETEROCYCLIC COMPOUNDS WITH PARASITICAL ACTIVITY | ZENECA LTD (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0660827-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY. | ZENECA LTD (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006777-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY | ZENECA LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |