SCHEMBL8752102

SCHEMBL8752102

CCc1cc(O)nc(O)c1NC=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11239261 0.74 CA12 (0.43) ALDH1A1LMNAMAPTHPGDCYP2C19
SCHEMBL28205320 0.73 ALDH1A1 (0.32) ALDH1A1CYP2C19
SCHEMBL28291367 0.73 GABRA1 (0.36) ALDH1A1LMNA
SCHEMBL28972322 0.69 ALDH1A1 (0.31) ALDH1A1LMNAMAPTHPGD
SCHEMBL11238333 0.69 ALDH1A1 (0.37) ALDH1A1MAPTHPGD
SCHEMBL4650747 0.68 KDM4E (0.36) ALDH1A1LMNAMAPTHPGDCYP2C19
SCHEMBL11313945 0.64 LMNA (0.35) ALDH1A1LMNAMAPTCYP2C19
SCHEMBL8492592 0.64 POLB (0.37) LMNA
SCHEMBL9488836 0.64
SCHEMBL5533366 0.63 GABRA1 (0.44) ALDH1A1LMNAMAPTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 EP disclosed
EP-0511246-B1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AG (DE) 1994-09-07 EP disclosed
EP-0388864-B1 Water-soluble, fibre-reactive dyes, method of their preparation and use HOECHST AG (DE) 1994-02-02 EP disclosed
US-5278292-A Aromatic sulfonyl water-soluble color materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-11 US disclosed
EP-0471702-B1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AG (DE) 1993-12-29 EP disclosed
US-5231172-A Water solubility HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
EP-0511246-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE. HOECHST AG (DE) 1992-11-04 EP disclosed
US-5128455-A WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed
EP-0361440-A1 Water soluble fibre-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-04 EP disclosed
EP-0354409-A1 Fibre-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-14 EP disclosed
US-4873320-A COLORFASTNESS; FOR COTTON AND CELLULOSE FIBER MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-10 US disclosed
EP-0212264-B1 COLOURED WATER SOLUBLE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-31 EP disclosed
EP-0271883-A2 Coloured water soluble compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-22 EP disclosed
US-4677199-A Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals BASF AKTIENGESELLSCHAFT (DE) 1987-06-30 US disclosed
EP-0212264-A1 Coloured water soluble compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed
EP-0119441-B1 REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS BASF Aktiengesellschaft (DE) 1987-02-25 EP disclosed
EP-0133270-A1 Reactive dyes BASF Aktiengesellschaft (DE) 1985-02-20 EP disclosed
EP-0119441-A2 Reactive dyes with substituted 4-fluoropyridaz-6-one groups BASF Aktiengesellschaft (DE) 1984-09-26 EP disclosed