SCHEMBL8752136

SCHEMBL8752136

O=C(O)Oc1ccc(Sc2ccc(OC(=O)O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.45
MAPT P10636 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
STS P08842 1/20 0.43
HPGD P15428 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
RAB9A P51151 1/20 0.43
ALDH1A1 P00352 3/20 0.42
ELANE P08246 1/20 0.41
NR1H2 P55055 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HSD17B10 Q99714 1/20 0.39
GAA P10253 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSP90AA1 P07900 1/20 0.38
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465132 0.84 LMNA (0.52) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL5355347 0.84 LMNA (0.61) LMNAMAPTMEN1KMT2AHPGD
SCHEMBL2290389 0.82 RAB9A (0.45) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL28670578 0.82 LMNA (0.50) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL3422384 0.81 ELANE (0.61) LMNAMAPTMEN1KMT2AHPGD
SCHEMBL11711919 0.79 PARP10 (0.38) LMNAMAPTMEN1KMT2AHPGD
SCHEMBL29817533 0.78 ALDH1A1 (0.46) LMNAMAPTMEN1KMT2ASTS
SCHEMBL2707663 0.78 HSD17B10 (0.71) LMNAMAPTMEN1KMT2AHPGD
SCHEMBL194962 0.77 HSD17B10 (0.59) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL18417 0.77 ELANE (0.54) LMNAMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP claimed
WO-2018050489-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2018-03-22 WO claimed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
WO-2018050489-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2018-03-22 WO disclosed
EP-0559667-B1 THERMOPLASTICALLY PROCESSABLE AROMATIC POLYETHER AMIDE HOECHST AG (DE) 1997-04-09 EP disclosed
EP-0496313-B1 Non-woven reinforced with a meltbinder HOECHST AG (DE) 1996-07-17 EP disclosed
EP-0496317-B1 Prepreg and fibre reinforced composites therefrom HOECHST AG (DE) 1996-04-10 EP disclosed
WO-1992016564-A1 BINARY ALLOYS ON THE BASIS OF POLYETHER AMIDES AND CYCLOOLEFIN POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-01 WO disclosed
EP-0496313-A1 Non-woven reinforced with a meltbinder HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-29 EP disclosed
EP-0496317-A2 Prepreg and fibre reinforced composites therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-29 EP disclosed
WO-1992009648-A1 THERMOPLASTICALLY PROCESSABLE AROMATIC POLYETHER AMIDE HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-11 WO disclosed