Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874549 | 0.78 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL21995339 | 0.76 | ACHE (0.52) | MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL28397007 | 0.76 | HTR2A (0.47) | TSHRHTR2A | |
| SCHEMBL2040946 | 0.74 | F2 (0.42) | TSHRPOLB | |
| SCHEMBL29575598 | 0.74 | METAP1 (0.49) | TSHRHTR2A | |
| SCHEMBL1119003 | 0.74 | METAP1 (0.49) | TSHRHTR2A | |
| SCHEMBL3290324 | 0.73 | MEN1 (0.68) | TSHRMEN1KMT2ADRD2ABL1 | |
| SCHEMBL3582634 | 0.73 | CACNA1G (0.35) | TSHRMEN1KMT2AALDH1A1POLB | |
| SCHEMBL3816899 | 0.73 | HTR2A (0.42) | HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL7828669 | 0.72 | MEN1 (0.66) | TSHRMEN1KMT2ADRD2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619208-A1 | IMIDAZOTRIAZINONE COMPOUNDS | Envivo Pharmaceuticals, Inc. (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040230-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |